Active Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A)

  • Catalog number
    RPU54909-50ug
  • Price
    Please ask
  • Size
    50ug
  • Estimated Turnaround Time
    6-11 business days
  • Gene Name
    NA
  • Alternative Names
    CD266; TNFRSF12-A; FN14; TWEAKR; Tumour Necrosis Factor Related Weak Inducer Of Apoptosis; Fibroblast growth factor-inducible immediate-early response protein 14
  • Source
    E. coli
  • Purity
    > 80%
  • Application
    Cell culture; Activity Assays.
  • Shipping Conditions
    Ice packs
  • Storage conditions
    Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
  • Shelf life
    1 year
  • Restriction
    For research use only. Not for diagnostic procedures.
  • Description
    Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Gene target
  • Gene symbol
    TNFRSF12A, IL12A
  • Short name
    Active Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A)
  • Species
    Homo sapiens (Human)
  • Alternative name
    functionnal Tumor Necrosis Factor Receptor supergroup, Member 12A (tumor necrosis factor receptor superfamily, member 12A)
  • Alternative to gene target
    tumor necrosis factor receptor superfamily, member 12A, TNFRSF12A and IDBG-11328 and ENSG00000006327 and 51330, protein binding, Cell surfaces, Tnfrsf12a and IDBG-143687 and ENSMUSG00000023905 and 27279, BT.20111 and IDBG-635818 and ENSBTAG00000012082 and 617439
  • Tissue
    tumor
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
  • Tree numbers
    • E01.370.225.500.383.910
    • E01.370.225.500.388.930
    • E05.200.500.383.910
    • E05.200.500.388.930
    • E05.242.383.910
    • E05.242.417.500
    • E05.337.550.200.800
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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