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Other name
Ryanodine receptor 2RYR-2RyR2hRYR-2,Cardiac muscle ryanodine receptor,Cardiac muscle ryanodine receptor-calcium release channel,Type 2 ryanodine recept,RYR2
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Immunogen
Recombinant human Ryanodine receptor 2 protein (901-1192AA)
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Verified reactivity
Human
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Verified applications
ELISA,IHC,IF
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Raised in
Rabbit
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Clonality
Polyclonal
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Protein number
Q92736
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Gene number
Please refer to GenBank
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NCBI number
Please refer to NCBI
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Purity
Protein G purified, >95%
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Storage recommendation
Aliquot and store at -20°C. Minimize freezing and thawing.
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Use before
1 year
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Shipping requirements
Blue ice
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Estimated production time
3-7 business days
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Supplementary information
Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.
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Notes
For research use only. Not for diagnostic procedures.
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Properties
If you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Group
Polyclonals and antibodies
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About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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French translation
anticorps
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Gene target
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Gene symbol
RYR2
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Short name
RYR2 Polyclonal Antibody
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Technique
Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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Label
Unconjugated
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Alternative name
ryanodine receptor 2 (cardiac) polyclonal (antibody to-)
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Alternative technique
polyclonals, antibodies
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Alternative to gene target
ryanodine receptor 2 (cardiac), ARVC2 and ARVD2 and RyR and RYR-2 and VTSIP, RYR2 and IDBG-107649 and ENSG00000198626 and 6262, calcium-induced calcium release activity, Plasma membranes, Ryr2 and IDBG-129559 and ENSMUSG00000021313 and 20191, RYR2 and IDBG-628576 and ENSBTAG00000022886 and 537376
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