Recombinant TNF Receptor Associated Factor 5 (TRAF5)
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Catalog number
RPU44057
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Price
Please ask
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Size
50 μg
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Verified reactivity
Homo sapiens (Human)
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Protein number
O00463
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Gene number
Please refer to GenBank
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Other name
RNF84; RING finger protein 84
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Protein origin
E.coli
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Protein region
Please contact us.
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Protein sequence
Please contact us.
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Information about sequence
Gln181~Arg437
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Expected molecular weight
33.9kDa
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Protein purity
≥ 98%
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Verified applications
SDS-PAGE; WB; ELISA; IP.
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Storage recommendation
Aliquot and store at -20°C. Minimize freezing and thawing.
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Use before
1 year
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Shipping requirements
Blue ice
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Estimated production time
7-11 business days
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Notes
For research use only. Not for diagnostic procedures.
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Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene
Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
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Gene target
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Gene symbol
TNF, TRAF5, TNFRSF1A, TNFRSF1B, LTBR
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Short name
Recombinant TNF Receptor Associated Factor 5 (TRAF5)
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. bioma advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Label
two N-terminal Tags, His-tag and T7-tag
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Alternative name
Rec. tumor necrosis factor Receptor Associated Factor 5 (tumor necrosis factor receptor-associated factor 5)
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Alternative technique
rec
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Alternative to gene target
TNF receptor-associated factor 5, MGC:39780 and RNF84, TRAF5 and IDBG-106494 and ENSG00000082512 and 7188, thioesterase binding, Plasma membranes, Traf5 and IDBG-208924 and ENSMUSG00000026637 and, TRAF5 and IDBG-638230 and ENSBTAG00000012020 and 507234
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Gene info
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Identity
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Gene
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Long gene name
tumor necrosis factor
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (TNF superfamily, member 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1986-01-01
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
Gene info
Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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