Recombinant Thyroid Hormone Receptor Beta (THRb)
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Catalog number
RPU51503
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Price
Please ask
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Size
10 μg
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Verified reactivity
Homo sapiens (Human)
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Protein number
P10828
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Gene name
Please refer to GenBank
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Other name
ERBA-BETA; ERBA2; GRTH; NR1A2; THR1; THRB1; THRB2; Erythroblastic Leukemia Viral(v-erb-a)Oncogene Homolog 2,Avian; Nuclear Receptor Subfamily 1,Group A,Member 2
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Protein origin
E.coli
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Protein region
Please contact us.
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Protein sequence
Please contact us.
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Information about sequence
Trp239~Glu457
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Expected molecular weight
28,46kDa
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Protein purity
≥ 95%
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Verified applications
SDS-PAGE; WB; ELISA; IP.
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Storage recommendation
Aliquot and store at -20°C. Minimize freezing and thawing.
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Use before
1 year
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Shipping requirements
Blue ice
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Estimated production time
7-11 business days
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Notes
For research use only. Not for diagnostic procedures.
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Description
Hormone releasing factors and releasing hormones are signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
THRB
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Short name
Recombinant Thyroid Hormone Receptor Beta (THRb)
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. bioma advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Label
two N-terminal Tags, His-tag and T7-tag
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Alternative name
Rec. Thyroid Hormone Receptor b (thyroid hormone receptor, b)
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Alternative technique
rec
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Alternative to gene target
thyroid hormone receptor, beta, C-ERBA-2 and C-ERBA-BETA and ERBA2 and GRTH and NR1A2 and PRTH and THR1 and THRB1 and THRB2, THRB and IDBG-22332 and ENSG00000151090 and 7068, thyroid hormone binding, nuclei, Thrb and IDBG-133569 and ENSMUSG00000021779 and 21834, THRB and IDBG-630420 and ENSBTAG00000017802 and 788329
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Tissue
thyroid
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Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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