Recombinant Purinergic Receptor P2X, Ligand Gated Ion Channel 7 (P2RX7)
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Catalog number
RPU53204
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Price
Please ask
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Size
200 μg
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Verified reactivity
Homo sapiens (Human)
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Protein number
Q99572
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Gene number
Please refer to GenBank
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Other name
P2X7; P2X Purinoceptor 7; ATP receptor; Purinergic receptor
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Protein origin
E.coli
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Protein region
Please contact us.
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Protein sequence
Please contact us.
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Information about sequence
Ser47~Val334
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Expected molecular weight
36.8kDa
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Protein purity
≥ 95%
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Verified applications
SDS-PAGE; WB; ELISA; IP.
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Storage recommendation
Aliquot and store at -20°C. Minimize freezing and thawing.
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Use before
1 year
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Shipping requirements
Blue ice
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Estimated production time
7-11 business days
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Notes
For research use only. Not for diagnostic procedures.
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Description
FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
P2RX7
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Short name
Recombinant Purinergic Receptor P2X, Ligand Gated Ion Channel 7 (P2RX7)
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. bioma advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Label
two N-terminal tags,his-tag and T7 tag
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Alternative name
Rec. Purinergic Receptor P2X, Ligand Gated Ion Channel 7 (purinergic receptor P2X, ligand-gated ion channel, 7)
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Alternative technique
rec
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Alternative to gene target
purinergic receptor P2X, ligand-gated ion channel, 7, P2X7, P2RX7 and IDBG-61253 and ENSG00000089041 and 5027, scaffold protein binding, nuclei, P2rx7 and IDBG-198410 and ENSMUSG00000029468 and 18439, P2RX7 and IDBG-633042 and ENSBTAG00000008948 and 286814
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Methods or procedures used to obtain samples of URINE.
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Tree numbers
- E01.370.225.998.762
- E05.200.998.762
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Qualifiers
ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data
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