POLH Polyclonal Antibody

• Catalog number
  CAC08013
• Price
  Please ask
• Size
  50 μg

• Other name
  DNA polymerase eta,RAD30 homolog A,Xeroderma pigmentosum variant type protein,POLH,RAD30,RAD30A,XPV
• Immunogen
  Recombinant Human DNA polymerase eta protein (408-609AA)
• Verified reactivity
  Human
• Verified applications
  ELISA,WB,IHC,IF. Recommended dilution:WB:1:500-1:5000,IHC:1:20-1:200,IF:1:50-1:200
• Raised in
  Rabbit
• Clonality
  Polyclonal
• Protein number
  Q9Y253
• Gene number
  Please refer to GenBank
• NCBI number
  Please refer to NCBI
• Purity
  Protein G purified, >95%
• Storage recommendation
  Aliquot and store at -20°C. Minimize freezing and thawing.
• Use before
  1 year
• Shipping requirements
  Blue ice
• Estimated production time
  3-7 business days
• Supplementary information
  DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci.
• Notes
  For research use only. Not for diagnostic procedures.
• Hyperlink
• Properties
  If you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  POLH  
• Gene symbol
  POLQ, POLH-AS1, POLH
• Short name
  POLH Polyclonal Antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Label
  Unconjugated
• Alternative name
  POLH polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:9186
• Gene
  POLQ
• Long gene name
  DNA polymerase theta
• Synonyms gene name
  • polymerase (DNA directed), theta
  • polymerase (DNA) theta
• Synonyms
  • POLH
• GenBank acession
  • AF052573
• Locus
  3q13.33
• Discovery year
  1999-04-15
• Entrez gene record
  10721
• Pubmed identfication
  • 10395804
• RefSeq identity
  • NM_199420
• Classification
  • DNA polymerases
• VEGA ID
  OTTHUMG00000159396

Gene info

• Identity
  HGNC:40459
• Gene
  POLH-AS1
• Long gene name
  POLH antisense RNA 1
• Synonyms
  • RP3-337H4.8
• Locus
  6p21.1
• Discovery year
  2017-08-30
• Pubmed identfication
  • 28839111
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:9181
• Gene
  POLH
• Long gene name
  DNA polymerase eta
• Synonyms gene name
  • polymerase (DNA directed), eta
  • polymerase (DNA) eta
• Synonyms
  • RAD30A
  • XP-V
• GenBank acession
  • AB024313
• Locus
  6p21.1
• Discovery year
  1997-09-12
• Entrez gene record
  5429
• Pubmed identfication
  • 20012583
  • 10385124
  • 10398605
• RefSeq identity
  • NM_006502
• Classification
  • DNA polymerases
  • Xeroderma pigmentosum complementation groups
• VEGA ID
  OTTHUMG00000014743
• Locus Specific Databases
  • LRG_470

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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