Rabbit/Mouse Monoclonal IgG Anti-PIN-Cocktail 1B -- P504S / p63 [13H4/EPR5701]
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Catalog numberPIN103-1.0
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Price:
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Size1 ml
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AvailabilityPlease contact us to check the availability
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Immunogen1. Recombinant human AMACR (P504S) protein, whole sequence; 2. Recombinant human p63 protein aa 1-203
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SpecificityHuman AMACR (P504S) protein, Alpha-Methylacyl CoA Racemase and human p63 nuclear protein
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Species reactivityHuman
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Product presentationAffinity purified antibodies in PBS, BSA, sodium azide (0.09%)**. Use antibody dilution buffer (e.g. Art. No. PU002) containing sufficient protein and preservative.
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Product categoryPrimary Antibody
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Antibody s raised inRabbit/Mouse
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Antibody s isotypeIgG
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Antibody s clone13H4/EPR5701
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Product is supplied asliquid concentrate
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Recommended concentration for use1:25-1:50
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Protein concentrationN/A
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Positive controlProstatic intraepithelial neoplasia
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PretreatmentUse formalin-fixed and paraffin-embedded sections; Retrieval conditions: Unmasking fluid T, TEC buffer (Tris/EDTA/Citrate) pH 8 (Art. No. DE005) in a pressure cooker at 100°C 20-40 minutes
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Tested applicationsIHC(C, P)
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Recommended secondary reagentDetection methods: VECTASTAIN Universal Elite ABC or ImmPRESS Rabbit IgG or other polymer kit detecting Rabbit IgG.
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Storage methodStore at 2-8°C
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UniProt numberGo to UniProt/SwissProt
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Litterature1. Jiang Z, Woda BA, Rock KL et al. (2001) P504S: a new molecular marker for the detection of prostate carcinoma. Am J Surg Pathol 25:1397-1404. 2. Weinstein MH, Signoretti S, Loda M (2002) Diagnostic utility of immunohistochemical staining for p63, a sensitive marker of prostatic basal cells. Mod Pathol. Dec;15(12):1302-8. 3. Luo J, Shan Zha, Wesley R, et al. (2002) Alpha methylacyl-CoA recemase, a new molecular marker for prostate cancer. Cancer Res 62:2220-2226.
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Tips*Gentaur's antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals. ** The preservative sodium azide is known to be poisonous and potentially hazardous to health. It should be handled only by trained staff. Despite of the product's low azide concentration it must be handled with care. Dispose according to regional rules!
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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AboutImmunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures. Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes. Rabbits are used for polyclonal antibody production by bio logo. Rabbit antibodies are very stable and can be stored for several days at room temperature. bio logo adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus, Oryctolagus cuniculus
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Gene target
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Gene symbolDYNLL1, AMACR
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Short nameBioprime
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TechniqueMouse monoclonal, Rabbit, anti-, Mouse, anti, IgG, antibody to, antibodies, IgGs, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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HostRabbit, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG. Rabbits
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IsotypeIgG, IgG
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SpeciesMouse, Mouses
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Alternative namePIN-Cocktail 1B -- P504S / p63
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Alternative techniquerabbit-anti, murine, antibodies, immunoglobulins
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Gene info
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Identity
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Gene
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Long gene namedynein light chain LC8-type 1
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Synonyms gene
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Synonyms gene name
- dynein, cytoplasmic, light polypeptide 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-12-18
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Dyneins, axonemal inner arm I1/f complex subunits
- Dynein 2 complex subunits
- Dynein 1 complex subunits
- Dyneins, axonemal outer arm complex subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namealpha-methylacyl-CoA racemase
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-10-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data