Rabbit Monoclonal IgG Anti-Synaptophysin, SYP (SP11) [SP11]
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Catalog numberSYP011-0.5
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Price:
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Size0.5 ml
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AvailabilityPlease contact us to check the availability
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ImmunogenSynthetic peptide corresponding to the C-terminus of human Synaptophysin
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SpecificitySynaptophysin, 38 kDa protein in neurectodermal tissue
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Species reactivityHuman, cattle, mouse, rat
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Product presentationTissue culture supernatant containing 0.2% BSA and 15 mM sodium azide**
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Product categoryPrimary Antibody
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Antibody s raised inRabbit
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Antibody s isotypeIgG
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Antibody s cloneSP11
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Product is supplied asliquid concentrate
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Recommended concentration for use1:50-1:100
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Protein concentrationN/A
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Positive controlAdrenal medulla, brain, appendix
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PretreatmentPre-treatment with unmasking fluids G (Art. No. DE007) or C (Art. No. DE000).
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Tested applicationsIHC(P)
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Recommended secondary reagentWe recommend the use of Gentaur's Universal Staining System DAB (Art. No. DA005) or AEC (Art.-No. AE005), if higher sensitivity is required VECTASTAIN Elite ABC (Art. No. PK-6101) or ABC AP (Art. No. AK-5001) systems are applicable as well as polymeric systems as long as they contain anti-rabbit conjugates.
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Storage methodStore at 2-8°C
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UniProt numberPGo to UniProt/SwissProt8247 (SYPH_HUMAN)
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Litterature1. Wiedenmann B. and Franke W.W. (1985) Identification and localization of synaptophysin, an integral membrane glykoprotein of Mr 38,000 characteristic of presynaptic vesicles. Cell 41; 1017-1028. 2. Wiedenmann B., Franke W.W., Kuhn C., Moll R., Gould V.E. (1986) Synaptophysin a marker protein for neuroendocrine cells and neoplasms. Proc. Natl. Acad. Sci (USA) 83; 3500-3504. 3. Buffa R., Rindi G., Sessa F., Gini A., Capella C., Jahn R., et al. (1988) Synaptophysin immunoreactivity and small clear vesicles in neuroendocrine cells and related tumours. Moel. Cellul. Probes 2; 367-381. 4. Stefaneanu L., Ryan N, Kovacs K. (1988) Immunocytochemical localization of synaptophysin in human hypophysis and pituitary adenomas. Arch. Pathol. Lab. Med. 112; 801-804
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Tips*Gentaur's antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals. ** The preservative sodium azide is known to be poisonous and potentially hazardous to health. It should be handled only by trained staff. Despite of the product's low azide concentration it must be handled with care. Dispose according to regional rules!
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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AboutImmunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures. Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes. Rabbits are used for polyclonal antibody production by bio logo. Rabbit antibodies are very stable and can be stored for several days at room temperature. bio logo adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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Gene target
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Gene symbolWDR87, SYP, SYP-AS1
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Short nameBioprime
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TechniqueRabbit, anti-, anti, IgG, antibody to, antibodies, IgGs, Monoclonals or monoclonal antibodies
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HostRabbit, Rabbits
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IsotypeIgG, IgG
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Alternative nameSynaptophysin, SYP (SP11)
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Alternative techniquerabbit-anti, antibodies, immunoglobulins
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Gene info
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Identity
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Gene
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Long gene nameWD repeat domain 87
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Synonyms
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GenBank acession
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Locus
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Discovery year2006-07-06
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Entrez gene record
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RefSeq identity
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Classification
- Armadillo like helical domain containing
- WD repeat domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesynaptophysin
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Synonyms
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GenBank acession
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Locus
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Discovery year1990-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MARVEL domain containing
- Synaptophysins
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameSYP antisense RNA 1
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Synonyms gene name
- SYP antisense RNA 1 (non-protein coding)
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Locus
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Discovery year2011-07-29
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Classification
- Antisense RNAs
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data