Rabbit Monoclonal IgG Anti-PAX-8 (Paired box protein 8) [ZR-1]

• Catalog number
  PAX008-0.5
• Price
  Please ask
• Size
  0.5 ml

• Availability
  Please contact us to check the availability
• Immunogen
  Synthetic peptide corresponding to the C-terminus of Human PAX8 protein
• Specificity
  PAX-8 protein
• Species reactivity
  Human, others not known
• Product presentation
  Tissue culture supernatant with 0.2% BSA and 15 mM sodium azide
• Product category
  Primary Antibody
• Antibody s raised in
  Rabbit
• Antibody s isotype
  IgG
• Antibody s clone
  ZR-1
• Product is supplied as
  liquid concentrate
• Recommended concentration for use
  1:50-1:100
• Positive control
  Thyroid carcinoma, Ovarian Clear Cell Carcinoma
• Pretreatment
  Pre-treatment of dewaxed tissue with heat-induced epitope retrieval (TRIS/EDTA, pH9.0 Ref. DE006) is recommended.
• Tested applications
  IHC (C,P)
• Recommended secondary reagent
  Anti-rabbit IgG:Biotin conjugate (code no. ZU101) in conjunction with Streptavidin-HRPO (code no. ZU054) or VECTOR ImmPress rabbit IgG Kit (code no. MP-7401).
• Storage method
  Store at 2-8°C
• UniProt number
  QGo to UniProt/SwissProt671Go to UniProt/SwissProt (PAX8_HUMAN)
• Litterature
  1. Poleev A., Fickenscher H., Mundlos S., Winterpacht A., Zabel B., Fidler A., Gruss P., Plachov D. PAX8, a human paired box gene: isolation and expression in developing thyroid, kidney and Wilms' tumors. Development 116:611-623(1992) [PubMed: 1337742] 2. Kozmik Z., Kurzbauer R., Doerfler P., Busslinger M. "Alternative splicing of Pax-8 gene transcripts is developmentally regulated and generates isoforms with different transactivation properties. Mol. Cell. Biol. 13:6024-6035(1993) [PubMed: 8413205] 3. Vilain C., Rydlewski C., Duprez L., Heinrichs C., Abramowicz M., Malvaux P., Renneboog B., Parma J., Costagliola S., Vassart G. Autosomal dominant transmission of congenital thyroid hypoplasia due to loss-of-function mutation of PAX8. J. Clin. Endocrin
• Tips
  Gentaur antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals. The preservative sodium azide has been added in very small quantities. Nevertheless, it may be harmful to health and the reagent should be used only by trained personnel. For waste disposal, please refer to national regulations.
• Other products
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• About
  Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures. Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes. Rabbits are used for polyclonal antibody production by bio logo. Rabbit antibodies are very stable and can be stored for several days at room temperature. bio logo adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  Monoclonal   PAX-8   Paired   box   protein   [ZR-1]  
• Gene symbol
  PAX8, PAX8-AS1, TRG-CCC8-1, SNORD114-8, TRQ-CTG8-1, TRV-CAC8-1, TRH-GTG1-8, EDC4, RNU6-8, TRR-CCT8-1
• Short name
  Research
• Technique
  Rabbit, anti-, anti, IgG, antibody to, antibodies, IgGs, Monoclonals or monoclonal antibodies
• Host
  Rabbit, Rabbits
• Isotype
  IgG, IgG
• Alternative name
  PAX-8 (Paired box protein 8)
• Alternative technique
  rabbit-anti, antibodies, immunoglobulins

Gene info

• Identity
  HGNC:8622
• Gene
  PAX8
• Long gene name
  paired box 8
• Synonyms gene name
  • paired box gene 8
• GenBank acession
  • X69699
• Locus
  2q14.1
• Discovery year
  1998-11-16
• Entrez gene record
  7849
• Pubmed identfication
  • 8431641
  • 7981748
• Classification
  • PRD class homeoboxes and pseudogenes
  • Paired boxes
• VEGA ID
  OTTHUMG00000128529

Gene info

• Identity
  HGNC:49271
• Gene
  PAX8-AS1
• Long gene name
  PAX8 antisense RNA 1
• GenBank acession
  • AK130275
• Locus
  2q14.1
• Discovery year
  2013-10-14
• Entrez gene record
  654433
• Pubmed identfication
  • 27225188
  • 29693272
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000153340

Gene info

• Identity
  HGNC:50798
• Gene
  TRG-CCC8-1
• Long gene name
  tRNA-Gly (anticodon CCC) 8-1
• Synonyms gene name
  • transfer RNA-Gly (CCC) 8-1
• Synonyms
  • tRNA-Gly-CCC-8-1
• GenBank acession
  • HG983805
• Locus
  1q21.1
• Discovery year
  2014-07-05
• Classification
  • Cytoplasmic transfer RNA pseudogenes

Gene info

• Identity
  HGNC:32996
• Gene
  SNORD114-8
• Long gene name
  small nucleolar RNA, C/D box 114-8
• Synonyms
  • 14q(II-8)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767584
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003200.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:34780
• Gene
  TRQ-CTG8-1
• Long gene name
  tRNA-Gln (CTG) 8-1
• Synonyms gene
  • TRNAQ19
• Synonyms gene name
  • transfer RNA glutamine 19 (anticodon CUG)
  • transfer RNA-Gln (CTG) 8-1
• Synonyms
  • tRNA-Gln-CTG-8-1
• GenBank acession
  • HG983729
• Locus
  1q21.2
• Discovery year
  2008-08-29
• Entrez gene record
  100189217
• Classification
  • Low confidence cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34704
• Gene
  TRV-CAC8-1
• Long gene name
  tRNA-Val (CAC) 8-1
• Synonyms gene
  • TRNAV16
• Synonyms gene name
  • transfer RNA valine 16 (anticodon CAC)
  • transfer RNA-Val (CAC) 8-1
• Synonyms
  • tRNA-Val-CAC-8-1
• GenBank acession
  • HG984123
• Locus
  1q21.1
• Discovery year
  2008-08-29
• Entrez gene record
  100189142
• Classification
  • Low confidence cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:34537
• Gene
  TRH-GTG1-8
• Long gene name
  tRNA-His (anticodon GTG) 1-8
• Synonyms gene
  • TRNAH2
  • TRH-GTG1-6
• Synonyms gene name
  • transfer RNA histidine 2 (anticodon GUG)
  • transfer RNA-His (GTG) 1-6
  • transfer RNA-His (GTG) 1-8
• Synonyms
  • tRNA-His-GTG-1-8
• GenBank acession
  • HG983837
• Locus
  15q21.1
• Discovery year
  2008-09-03
• Entrez gene record
  100188988
• Classification
  • Cytoplasmic transfer RNAs

Gene info

• Identity
  HGNC:17157
• Gene
  EDC4
• Long gene name
  enhancer of mRNA decapping 4
• Synonyms
  • RCD-8
  • Ge-1
  • HEDLS
• GenBank acession
  • U17474
• Locus
  16q22.1
• Discovery year
  2006-07-07
• Entrez gene record
  23644
• Pubmed identfication
  • 9067524
• RefSeq identity
  • NM_014329
• Classification
  • WD repeat domain containing
• VEGA ID
  OTTHUMG00000137543

Gene info

• Identity
  HGNC:34285
• Gene
  RNU6-8
• Long gene name
  RNA, U6 small nuclear 8
• Synonyms
  • U6-8
• Locus
  14q12
• Discovery year
  2008-06-10
• Entrez gene record
  101954278
• Pubmed identfication
  • 12711679
• RefSeq identity
  • NR_104088
• Classification
  • Small nuclear RNAs

Gene info

• Identity
  HGNC:35077
• Gene
  TRR-CCT8-1
• Long gene name
  tRNA-Arg (anticodon CCT) 8-1
• Synonyms gene
  • TRNAR32P
• Synonyms gene name
  • transfer RNA arginine 32 (anticodon CCU) pseudogene
  • transfer RNA-Arg (CCT) 8-1
• Synonyms
  • tRNA-Arg-CCT-8-1
• GenBank acession
  • HG983613
• Locus
  1q21.2
• Discovery year
  2008-08-29
• Entrez gene record
  100189502

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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