Glucagon (19-29), human

Description

Glucagon is a peptide hormone, secreted by the pancreas, that raises blood glucose levels. Miniglucagon (Glucagon 19–29) is a potent and efficient inhibitor of secretagogue-induced ins release through a Ca2+ Pathway. Miniglucagon is a novel local regulator of the pancreatic islet physiology. Some evidence has shown that glucagon processing into miniglucagon may be essential for the positive inotropic effect of glucagon on heart contraction.
Similar products
Formula

C61H89N15O18S
Molecular Weight

1352.51
Cas no

64790-15-4
Additional description

Glucagon gene and the glucagon like peptide or GLP1 gene are peptide hormones, produced by alpha cells of the pancreas to raise the concentration of glucose in the blood as opposite of insulin, which lowers the glucose. Anti human glucagon and glp1 antibodies are used to study diabetes.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Gene target

Glucagon 19-29
Gene symbol

SNORD114-29, SNORD115-29, SNORD116-29, IGLV3-29, IGHV3-29, IGKV2-29, PIRC99, PIRC98
Short name

Glucagon (19-29),
Species

Human, Humans
Alternative name

Glucagon (19-29), H. sapiens

Identity

HGNC:5590
Gene

IGHV3-29
Long gene name

immunoglobulin heavy variable 3-29 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable 3-29
- immunoglobulin heavy variable 3-29 pseudogene
GenBank acession
- M99662
Locus

14q32.33
Discovery year

2000-04-04
Entrez gene record

28440
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000188328