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Available ordering format
Liquid in 0.9% NaCl, 0.02% sodium azide
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Immunogen
KLH-conjugated synthetic peptide: ACCSPPPDYNSVVLYSTPPI, corresponding to C-terminal of human VEGF Receptor 1. Accession number P17948.
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Raised in
Chicken
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Clonality
Polyclonal
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Clone
Polyclonal
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Purification
Total IgY
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How to reconstitute
See included datasheet or contact our support service
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Storage condition
4 to 8°C.
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Verified applications
ELISA (ELISA), immunohistochemistry (IHC)
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Connected products
AS10 1574 | Anti-VEGFR3 | Vascular endothelial growth factor receptor 3 Secondary antibodies
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Recommended dilutions for use
1:1000 (ELISA), 1:10 000 (IHC)
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Molecular weight expected аpparent
150.8 kDa
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Verified reactivity
human
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Possible reactivity
mouse, rat, frog
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No reactivity
no confirmed exceptions from predicted reactivity known at the moment
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Supplementary information
ELISA assay was done against peptide used to elicit this antibody.
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References
to be added when available
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Scientific context
Vascular endothelial growth factor receptor 1 are receptors for vascular endothelial growth factor (VEGF). (VEGF) is an important signaling protein involved in both vasculogenesis (the formation of the circulatory system) and angiogenesis (the growth of blood vessels from pre-existing vasculature). It have effects on a limited number of other cell types (e.g. stimulation monocyte/macrophage migration). VEGF also enhances microvascular permeability.
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Notes
None
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Protein number
P17948
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TAIR number
Refer to NCBI
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Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.