TF, transferrin

  • Catalog number
    AS10 1370
  • Price
    Please ask
  • Size
    1 mg
  • Available ordering format
    Liquid
  • Immunogen
    human transferrin AAB22049
  • Raised in
    Goat
  • Clonality
    Polyclonal
  • Clone
    Polyclonal
  • Purification
    Affinity purified
  • How to reconstitute
    See included datasheet or contact our support service
  • Storage condition
    2-8 °C.
  • Verified applications
    This antibody is suitable for all immunoassay applications
  • Connected products
    IMS02-020-322 | TF | Transferrin, hen antibodyIMS06-020-323 | TF | Transferrin labelled with biotin, hen antibodyanti-goat secondary antibodies
  • Recommended dilutions for use
    The optimal working dilution should be determined by the investigator.
  • Molecular weight expected аpparent
    77 kDa
  • Verified reactivity
    human transferrin
  • Possible reactivity
    primates
  • No reactivity
    no confirmed exceptions from predicted reactivity known in the moment
  • Supplementary information
    Affinity purified using solid phase human Transferrin. Antibody concentration is > 4.5 mg/ml (E 1% at 280 nm = 13.0).Antibody is supplied in 10 mM sodium phosphate, 0.15 M sodium chloride, pH 7.2. Contains 0.05% (w/v) sodium azide as preservative. Antibody purity is > 95% based on SDS-PAGE.
  • References
    to be added when available
  • Scientific context
    Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesised in the liver and consists of two domains, each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in haemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. The function of transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. In addition to its function in iron transport, this protein may also have a physiologic role as granulocyte/pollen binding protein (GPBP) involved in the removal of certain organic matter/allergins from serum.
  • Notes
    None
  • Protein number
    Refer to NCBI
  • TAIR number
    Refer to NCBI
  • Gene target
  • Gene symbol
    TF
  • Short name
    TF, transferrin
  • Alternative name
    TF, transferrin
Gene info
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