F7, Coagulation factor VII

  • Catalog number
    IMS01-118-307
  • Price
    Please ask
  • Size
    100 µl (11 mg/ml)
  • Available ordering format
    Liquid in 0.9% NaCl, 0.1% sodium azide
  • Immunogen
    Purified full length recombinant protein P08709
  • Raised in
    Hen
  • Clonality
    Polyclonal
  • Clone
    Polyclonal
  • Purification
    Total IgY
  • How to reconstitute
    See included datasheet or contact our support service
  • Storage condition
    store at 4°C; make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.
  • Verified applications
    Western blot (WB)
  • Connected products
    AS00 001 | anti-Coagulation factor VIIa IMS01-015-308 | anti-Coagulation factor VIII AS05 058 | anti-Coagulation factor IXIMS01-137-306 | anti-Coagulation factor XIISecondary antibodies
  • Recommended dilutions for use
    1: 5 000 - 1: 10 000 with standard ECL (WB), 1: 1000 - 1: 5 000 (ELISA)
  • Molecular weight expected аpparent
    52 kDa
  • Verified reactivity
    human
  • Possible reactivity
    primates
  • No reactivity
    no confirmed exceptions from predicted reactivity known in the moment
  • Supplementary information
    the antibody, in dilution 1: 10 000, will detect 1 ng of factor VII in immunoblotting
  • References
    to be added when available
  • Scientific context
    Factor VII is a 52 kDa multi-domain, single chain plasma glycoprotein synthesised in the liver and having abnormal circulating concentration of between 400 and 600 g/L. It is essential for blood coagulation. Factor VII is converted to the active, two chain, serine protease Factor VIIa through cleavage by thrombin, Factor Xa, Factor IXa or Factor XIIa. Factor VIIa converts Factor X to Factor Xa, which in turn converts prothrombin to thrombin.
  • Notes
    he IgY fraction is isolated by a two-step PEG precipitation procedure followed by ammonium sulphate precipitation
  • Protein number
    P08709
  • TAIR number
    Refer to NCBI
  • Description
    Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
  • Gene target
  • Gene symbol
    MARCHF7, IGLVVII-41-1, SYT7
  • Short name
    F7, Coagulation factor VII
  • Alternative name
    coagulation factor VII (serum prothrombin conversion accelerator), Coagulation factor VII
  • Alternative to gene target
    coagulation factor VII (serum prothrombin conversion accelerator), SPCA, F7 and IDBG-52192 and ENSG00000057593 and 2155, serine-type peptidase activity, Extracellular, F7 and IDBG-134155 and ENSMUSG00000031443 and 14068, F7 and IDBG-634312 and ENSBTAG00000007411 and 617960
Gene info
  • Identity
  • Gene
  • Long gene name
    membrane associated ring-CH-type finger 7
  • Synonyms gene
  • Synonyms gene name
    • axotrophin
    • membrane-associated ring finger (C3HC4) 7
    • membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2001-12-17
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Ring finger proteins
    • Membrane associated ring-CH-type fingers
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin lambda variable (VII)-41-1 (pseudogene)
  • Synonyms gene name
    • immunoglobulin lambda variable (VII)-41-1
    • immunoglobulin lambda variable (VII)-41-1 pseudogene
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2001-05-15
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin lambda locus at 22q11.2
  • VEGA ID
Gene info
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