C1-inh, C1 Inhibitor

• Catalog number
  AS10 1314
• Price
  Please ask
• Size
  1 mg

• Available ordering format
  Liquid
• Immunogen
  human C1 Inhibitor CAA30314
• Raised in
  Sheep
• Clonality
  Polyclonal
• Clone
  Polyclonal
• Purification
  Affinity purified
• How to reconstitute
  See included datasheet or contact our support service
• Storage condition
  2-8 °C.
• Verified applications
  This antibody is suitable for all immunoassay applications
• Connected products
  anti-sheep secondary antibodiesanti-sheep secondary antibodies
• Recommended dilutions for use
  The optimal working dilution should be determined by the investigator.
• Molecular weight expected аpparent
  see datasheet
• Verified reactivity
  human C1 Inhibitor
• Possible reactivity
  n.a.
• No reactivity
  no confirmed exceptions from predicted reactivity known in the moment
• Supplementary information
  Affinity purified using solid phase human C1 inhibitor. Antibody concentration is > 4.5 mg/ml (E 1% at 280 nm = 13.0).Antibody is supplied in 10 mM sodium phosphate, 0.15 M sodium chloride, pH 7.2. Contains 0.05% (w/v) sodium azide as preservative. Antibody purity is > 95% based on SDS-PAGE.
• References
  to be added when available
• Scientific context
  C1 inhibitor (C1-inh or C1 esterase inhibitor) functions as inhibitor of complement system in human serum.
• Notes
  None
• Protein number
  Refer to NCBI
• TAIR number
  Refer to NCBI
• Hyperlink
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  C1-inh   Inhibitor  
• Gene symbol
  SNAR-C1, TRGC1, PFDN4, TNS2, ARHGAP4, MAGEC1, SERPING1, PLAAT1
• Short name
  C1-inh, C1 Inhibitor
• Alternative name
  C1-inh, C1 suppressor

Gene info

• Identity
  HGNC:34319
• Gene
  SNAR-C1
• Long gene name
  small NF90 (ILF3) associated RNA C1
• Synonyms gene name
  • small ILF3/NF90-associated RNA C1
• GenBank acession
  • EU071066
• Locus
  19q13.32
• Discovery year
  2008-07-03
• Entrez gene record
  100170225
• Pubmed identfication
  • 17855395
• RefSeq identity
  • NR_024220
• Classification
  • Small NF90 (ILF3) associated RNAs

Gene info

• Identity
  HGNC:12275
• Gene
  TRGC1
• Long gene name
  T cell receptor gamma constant 1
• Synonyms gene
  • TCRGC1
• Synonyms gene name
  • TCRGC1
• Synonyms
  • C1
• Synonyms name
  • T-cell receptor, gamma, constant region C1
• GenBank acession
  • M14996
• Locus
  7p14.1
• Discovery year
  1989-05-30
• Entrez gene record
  6966
• Pubmed identfication
  • 2879283
• RefSeq identity
  • NG_001336
• Classification
  • T cell receptor gamma locus at 7p14
• VEGA ID
  OTTHUMG00000155219

Gene info

• Identity
  HGNC:8868
• Gene
  PFDN4
• Long gene name
  prefoldin subunit 4
• Synonyms gene name
  • prefoldin 4
• Synonyms
  • PFD4
  • C-1
  • C1
• GenBank acession
  • U41816
• Locus
  20q13.2
• Discovery year
  1998-08-06
• Entrez gene record
  5203
• Pubmed identfication
  • 9630229
  • 8744932
• RefSeq identity
  • NM_002623
• Classification
  • Prefoldin subunits
• VEGA ID
  OTTHUMG00000032775

Gene info

• Identity
  HGNC:19737
• Gene
  TNS2
• Long gene name
  tensin 2
• Synonyms gene
  • TENC1
• Synonyms gene name
  • tensin like C1 domain-containing phosphatase
  • tensin like C1 domain containing phosphatase (tensin 2)
• Synonyms
  • KIAA1075
  • C1-TEN
• GenBank acession
  • AF518729
• Locus
  12q13.13
• Discovery year
  2002-12-09
• Entrez gene record
  23371
• RefSeq identity
  • NM_170754
• Classification
  • PTEN protein phosphatases
  • SH2 domain containing
  • C2 tensin-type domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000169730

Gene info

• Identity
  HGNC:674
• Gene
  ARHGAP4
• Long gene name
  Rho GTPase activating protein 4
• Synonyms
  • KIAA0131
  • C1
  • p115
  • RhoGAP4
  • SrGAP4
• Synonyms name
  • Rho-GAP hematopoietic protein C1
• GenBank acession
  • X78817
• Locus
  Xq28
• Discovery year
  1997-08-28
• Entrez gene record
  393
• Pubmed identfication
  • 8570618
• RefSeq identity
  • NM_001666
• Classification
  • AH/BAR family Rho GTPase activating proteins
  • F-BAR domain containing
• VEGA ID
  OTTHUMG00000024226
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:6812
• Gene
  MAGEC1
• Long gene name
  MAGE family member C1
• Synonyms gene name
  • melanoma antigen family C1
• Synonyms
  • MAGE-C1
  • CT7
  • MGC39366
  • CT7.1
• Synonyms name
  • cancer/testis antigen family 7, member 1
• GenBank acession
  • AF064589
• Locus
  Xq27.2
• Discovery year
  1999-04-23
• Entrez gene record
  9947
• Pubmed identfication
  • 9485030
  • 9618514
• RefSeq identity
  • NM_005462
• Classification
  • MAGE family
• VEGA ID
  OTTHUMG00000022569
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:1228
• Gene
  SERPING1
• Long gene name
  serpin family G member 1
• Synonyms gene
  • C1NH
• Synonyms gene name
  • serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary)
  • serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
• Synonyms
  • C1IN
  • C1-INH
  • HAE1
  • HAE2
  • C1INH
• Synonyms name
  • plasma protease C1 inhibitor
  • angioedema, hereditary
  • C1-inhibitor
• GenBank acession
  • X54486
• Locus
  11q12.1
• Discovery year
  2001-06-22
• Entrez gene record
  710
• Pubmed identfication
  • 2026152
  • 24172014
• RefSeq identity
  • NM_000062
• Classification
  • Complement system regulators and receptors
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000150304
• Locus Specific Databases
  • SERPING1base: Mutation registry for Hereditary angioedema
  • LRG_105

Gene info

• Identity
  HGNC:14922
• Gene
  PLAAT1
• Long gene name
  phospholipase A and acyltransferase 1
• Synonyms gene
  • HRASLS
• Synonyms gene name
  • HRAS like suppressor
• Synonyms
  • H-REV107
  • HRASLS1
  • A-C1
  • PLA/AT1
  • PLAAT-1
• Synonyms name
  • phospholipase A/acyltransferase 1
• GenBank acession
  • AB030816
• Locus
  3q29
• Discovery year
  2001-04-10
• Entrez gene record
  57110
• Pubmed identfication
  • 21880860
• Classification
  • Phospholipase A and acyltransferase family
• VEGA ID
  OTTHUMG00000156104

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