Poly (ADP-ribose) Polymerase (PARP), 116kD, Clone: A6.4.12, Mouse Monoclonal antibody-Rat, Hamster, Xenopus, Drosophila, Mouse
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Catalog numberOBT0384
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PricePlease ask
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Size2 ml
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Alternative name 1Poly (ADP-ribose) Polymerase (PARP), 116kD, Clone: A6.4.12, Mab anti-Rat, Hamster, Xenopus, Drosophila, Mouse
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Alternative name 2Poly (ADP-ribose) Polymerase (PARP), 116kD, Clone: A6.4.12, Mab antibody-Rat, Hamster, Xenopus, Drosophila, Mouse
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Alternative name 3Poly (ADP-ribose) Polymerase (PARP), 116kD, Clone: A6.4.12, Mab antibody-Rattus norvegicustus norvegicus, Hamster, Xenopus, Drosophila, Mus musculus
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Alternative name 4anti-Poly ADP-ribose Polymerase PARP 116kD Clone: A6.4.12 Drosophila
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Alternative name 5Poly ADP-ribose Polymerase PARP 116kD Clone: A6.4.12 Drosophila
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ClonalityMonoclonal Antibody
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DescriptionThis is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against. If used correctly and according the protocol, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications. Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches; in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required.
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Storage and handlingGenerally, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for longer periods - at -20 . Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°C.
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AdvisoryTo keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided. For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container. Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom.
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PropertiesIf you buy Antibodies supplied by accurate-monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Armenian of Syrian hamster monoclonal IgGs are useful antibodies for double staining your IHC samples. Using mabs or monoclonal antibodies has a lot of advantages for Flow cytometry.
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AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus, Rattus norvegicus
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French translationanticorps
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Gene target
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Gene symbolWDTC1, ADPGK, TNKS2, TIPARP, PARP1, PARP12, TNKS
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Short namePoly (ADP-ribose) Polymerase (PARP), 116kD, Clone: A6 4 12, Mouse Monoclonal antibody- , , Xenopus, , Mouse
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TechniqueMouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Hostmouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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SpeciesMouse, Drosophila subspecies d. Megalonaster or the fruit fly is used in genetic research because of the short life cycle and the possibility of knock-out and knock-ins with Cas9 for ends-in gene targets like CRISPR.Cas9 and TALEN vectors . Drosophilas, Hamsters, Mouses, Rats, Xenopuses
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Alternative namePoly (ADP-ribose) polymerizing enzyme (PARP), 116kD, clonality: A6.4.12, Mouse monoclonal (antibody to-)-Rat, Hamster, Xenopus, Drosophila, Mouse
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Alternative techniqueantibodies, murine
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Gene info
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Identity
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Gene
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Long gene nameWD and tetratricopeptide repeats 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-12-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- WD repeat domain containing
- Tetratricopeptide repeat domain containing
- DDB1 and CUL4 associated factors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameADP dependent glucokinase
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-09-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametankyrase 2
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Synonyms gene name
- tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-05-10
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Entrez gene record
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RefSeq identity
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Classification
- Poly(ADP-ribose) polymerases
- Sterile alpha motif domain containing
- Ankyrin repeat domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTCDD inducible poly(ADP-ribose) polymerase
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Synonyms gene name
- TCDD-inducible poly(ADP-ribose) polymerase
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-12-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Poly(ADP-ribose) polymerases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namepoly(ADP-ribose) polymerase 1
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Synonyms gene
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Synonyms gene name
- ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)
- poly (ADP-ribose) polymerase family, member 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Zinc fingers PARP-type
- Zinc fingers
- Poly(ADP-ribose) polymerases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namepoly(ADP-ribose) polymerase family member 12
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Synonyms gene
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Synonyms gene name
- zinc finger CCCH-type domain containing 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-12-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Poly(ADP-ribose) polymerases
- Zinc fingers CCCH-type
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametankyrase
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Synonyms gene name
- tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-01-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Poly(ADP-ribose) polymerases
- Sterile alpha motif domain containing
- Ankyrin repeat domain containing
- MicroRNA protein coding host genes
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data