CA-125 Ovarian Cancer Antigen (Protein Core), Clone: Ov185:1, Mouse Monoclonal antibody-Human; frozen/paraffin, IH
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Catalog numberMEDCLA687
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Price:
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Size7 ml
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Alternative name 1CA-125 Ovarian Cancer Antigen (Protein Core), Clone: Ov185:1, Mab anti-Human; frozen/paraffin, IH
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Alternative name 2CA-125 Ovarian Cancer Antigen (Protein Core), Clone: Ov185:1, Mab antibody-Human; frozen/paraffin, IH
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Alternative name 3CA-125 Ovarian Cancer Antigen (Protein Core), Clone: Ov185:1, Mab antibody-Homo sapiens; frozen/paraffin, IH
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Alternative name 4anti-CA-125 Ovarian Cancer Antigen Protein Core Clone: Ov185:1
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Alternative name 5CA-125 Ovarian Cancer Antigen Protein Core Clone: Ov185:1
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ClonalityMonoclonal Antibody
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DescriptionThis is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against. If used correctly and according the protocol, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications. Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches; in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required.
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Storage and handlingGenerally, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for longer periods - at -20 . Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°C.
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AdvisoryTo keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided. For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container. Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom.
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PropertiesIf you buy Antibodies supplied by accurate-monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional descriptionAntigens are peptides or recombinant or native dependent on the production method.
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AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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French translationanticorps
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Gene target
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Gene symbolMUC16, MED31, CA2, NBR1, CA10, OR5D2P
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Short nameCA-125 Ovarian Cancer Antigen (Protein Core), Clone: Ov185:1, Mouse Monoclonal antibody- ; frozen/paraffin, IH
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TechniqueMouse monoclonal, Antibody, paraffin, antigen, frozen, Mouse, antibodies against human proteins, antibodies for, antigenes, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Hostmouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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SpeciesHuman, Humans, Mouses
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Alternative nameCA-125 Ovarian Cancer protein (Protein Core), clonality: Ov185:1, Mouse monoclonal (antibody to-)-H. sapiens; -25°C frozen/paraffin, IH
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Alternative techniqueantibodies, antigenes, murine
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Tissuefrozen, ovarian
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Diseasecancer
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Gene info
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Identity
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Gene
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Long gene namemucin 16, cell surface associated
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-07-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Mucins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemediator complex subunit 31
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Synonyms gene name
- mediator of RNA polymerase II transcription, subunit 31 homolog (S. cerevisiae)
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-11-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Mediator complex
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecarbonic anhydrase 2
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Synonyms gene name
- carbonic anhydrase II
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Carbonic anhydrases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameNBR1 autophagy cargo receptor
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Synonyms gene
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Synonyms gene name
- membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125)
- neighbor of BRCA1 gene 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1994-08-29
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Zinc fingers ZZ-type
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecarbonic anhydrase 10
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Synonyms gene name
- carbonic anhydrase X
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-07-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Carbonic anhydrases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameolfactory receptor family 5 subfamily D member 2 pseudogene
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Synonyms gene
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Synonyms gene name
- olfactory receptor, family 5, subfamily D, member 11 pseudogene
- olfactory receptor, family 5, subfamily D, member 2 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-11-09
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Entrez gene record
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Pubmed identfication
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Classification
- Olfactory receptors, family 5
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Thinly cut sections of frozen tissue specimens prepared with a cryostat or freezing microtome.
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Tree numbers
- E01.370.225.500.620.530.160.260
- E01.370.225.750.600.530.160.260
- E05.200.500.620.530.160.260
- E05.200.750.600.530.160.260
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data