Human IL8 CRISPR Knock Out 293T Cell Line

• Catalog number
  K1077151
• Price
  Please ask
• Size
  1x10^6 cells/1.0ml

• Cell line type
  293T
• NCBI number
  NM_000584
• Availability
  Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
• Ordering
  If you wish to order this product, please include the catalogue number #K1077151in your purchase order among with your shipping and billing information.
• Technical file
  Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
• Notes
  Designed for Research Use Only. Manufactured in Canada.
• Other products
• Description
  For cells, cell lines and tissues in culture till half confluency.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Gene
  Interleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells. Endothelial cells store IL-8 in their storage vesicles, the Weibel-Palade bodies. In humans, the interleukin-8 proteins encoded by the IL8 gene. IL-8 is initially produced as a precursor peptide of 99 amino acids long which then undergoes cleavage to create several active IL-8 isoforms. In culture, a 72 amino acid peptide is the major form secreted by macrophages. Recombinant, rec. E. coli interleukin-8 for cell culture or antibody production.

• Gene target
  IL8   CRISPR   Knock   Out   Line  
• Gene symbol
  CXCL8
• Short name
  IL8 CRISPR Knock Out Line
• Technique
  CV40 transformed cell line or 293tsA1609neo from human kidney 293 cells delivered as 1.
• Species
  Human, Humans
• Alternative name
  H. sapiens interleukin 8 CRISPR Knock Out 293T cellular Line
• Alternative to gene target
  interleukin 8, GCP-1 and GCP1 and IL8 and LECT and LUCT and LYNAP and MDNCF and MONAP and NAF and NAP-1 and NAP1, IL8 and IDBG-23954 and ENSG00000169429 and 3576, chemokine activity, Extracellular, IL8 and IDBG-643010 and ENSBTAG00000019716 and 280828
• Tissue
  cell

Gene info

• Identity
  HGNC:6025
• Gene
  CXCL8
• Long gene name
  C-X-C motif chemokine ligand 8
• Synonyms gene
  • IL8
• Synonyms gene name
  • interleukin 8
  • chemokine (C-X-C motif) ligand 8
• Synonyms
  • SCYB8
  • LUCT
  • LECT
  • MDNCF
  • TSG-1
  • IL-8
  • NAP-1
  • 3-10C
  • MONAP
  • AMCF-I
  • LYNAP
  • NAF
  • b-ENAP
  • GCP-1
  • K60
  • GCP1
  • NAP1
• Synonyms name
  • neutrophil-activating peptide 1
  • granulocyte chemotactic protein 1
  • monocyte-derived neutrophil chemotactic factor
  • lung giant cell carcinoma-derived chemotactic protein
  • tumor necrosis factor-induced gene 1
  • monocyte-derived neutrophil-activating peptide
  • lymphocyte derived neutrophil activating peptide
  • beta endothelial cell-derived neutrophil activating peptide
  • alveolar macrophage chemotactic factor I
• GenBank acession
  • Y00787
• Locus
  4q13.3
• Discovery year
  1989-06-30
• Entrez gene record
  3576
• Pubmed identfication
  • 1427896
  • 11178128
• RefSeq identity
  • NM_000584
• Classification
  • Chemokine ligands
  • Interleukins
• VEGA ID
  OTTHUMG00000151316

MeSH Data

• Name
  Transformation, Bacterial
• Concept
  Scope note: The heritable modification of the properties of a competent bacterium by naked DNA from another source. The uptake of naked DNA is a naturally occuring phenomenon in some bacteria. It is often used as a GENE TRANSFER TECHNIQUE.
• Tree numbers
  • E05.393.350.810.500
• Qualifiers
  immunology, physiology, ethics, drug effects, radiation effects, genetics

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