Human Interleukin 6 (IL6)

Long name

Recombinant Human Interleukin 6 (IL6)
Gene name

Interleukin 6
Category

Recombinant proteins
Storage and handling

For short term storage the vial may be kept refrigerated in the temperature range of 1 to 6 degrees Celcius. For long term storage, keep the protein frozen at -20 deg. C. Avoid cycles of freezing and twaing as they may denaturate the peptide chains of the protein, thus changing its structure and properties.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Gene

Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the IL6 gene. Recombinant, rec. E. coli interleukin-6 for cell culture or antibody production.

Gene target

Interleukin IL6
Gene symbol

IL6-AS1, IL6, CEBPD
Short name

Recombinant Interleukin 6
Species

Human, Humans
Alternative name

Human Interleukin 6 (IL6)
Alternative to gene target

interleukin 6 (interferon, beta 2), BSF2 and HGF and HSF and IFNB2 and IL-6, IL6 and IDBG-9462 and ENSG00000136244 and 3569, growth factor activity, Extracellular, Il6 and IDBG-144970 and ENSMUSG00000025746 and 16193, IL6 and IDBG-630280 and ENSBTAG00000014921 and 280826

Identity

HGNC:6018
Gene

IL6
Long gene name

interleukin 6
Synonyms gene
- IFNB2
Synonyms gene name
- interleukin 6 (interferon, beta 2)
Synonyms
- IL-6
- BSF2
- HGF
- HSF
Synonyms name
- interferon, beta 2
GenBank acession
- M18403
Locus

7p15.3
Discovery year

1986-01-01
Entrez gene record

3569
Pubmed identfication
- 3294161
RefSeq identity
- NM_000600
Classification
- Interleukins
- Interferons
- Interleukin 6 type cytokine family
VEGA ID

OTTHUMG00000023178

Identity

HGNC:1835
Gene

CEBPD
Long gene name

CCAAT enhancer binding protein delta
Synonyms gene name
- CCAAT/enhancer binding protein (C/EBP), delta
- CCAAT/enhancer binding protein delta
Synonyms
- CRP3
- CELF
- C/EBP-delta
- NF-IL6-beta
Locus

8q11.21
Discovery year

1992-06-24
Entrez gene record

1052
Pubmed identfication
- 1840554
- 1884998
RefSeq identity
- NM_005195
Classification
- Basic leucine zipper proteins
- CCAAT/enhancer binding proteins
VEGA ID

OTTHUMG00000162290