Engrailed Homeobox 2 Protein (OVA)
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Catalog number
abx165529
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Price
Please ask
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Size
10 μg
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Category
Proteins And Peptides
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Clonality
N/A
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Raised in
N/A
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Target
Engrailed Homeobox 2 Protein
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Immunogen
see included datasheet or contact us
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Species reactivity
Human, Mouse, Rat (for other species please inquire)
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Purification
Affinity purified
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Applications
WB (for other applications please contact us)
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Stock availability
Shipped within 5-12 working days.
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Storage conditions
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
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Footnote
This product is for research use only.
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Gene
Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.
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