PRKCA(Thr637) Antibody
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Catalog numberbs-5574R
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PricePlease ask
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Size0.1ml
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Long namePRKCA(Thr637) Primary Polyclonal Antibody
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Also known asPRKCA(Thr637) PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenPRKCA Thr637
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SpecificityThis is a highly specific antibody against PRKCA Thr637.
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Modification sPhosphorylation
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Modification site sThr637
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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SourceKLH conjugated synthetic phosphopeptide derived from human PRKCA around the phosphorylation site of Thr637
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Gene ID number5578
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenProtein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesPRKCAphospho T637; rotein Kinase C; AAG6; Aging associated gene 6; MGC129900; MGC129901; MGC41878; MGC57564; PKC B; PKC beta; PKC zeta; PKC2; PKCB; PKCC; PKCD; PKCE; PKCG; PRKACA; PRKC A; PRKC G; PRKCA; PRKCB; PRKCB1; PRKCB2; PRKCD; PRKCE; PRKCG; PRKCZ ; Protein kinase C alpha; Protein kinase C alpha type; Protein Kinase C; Protein kinase C beta 1; Protein kinase C beta 1 polypeptide; Protein kinase C beta; Protein kinase C beta type; Protein kinase C delta; Protein kinase C epsilon; Protein kinase C gamma; Protein kinase C gamma type; Protein kinase C zeta; SCA14; Spinocerebellar ataxia 14.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolPRKCA-AS1, PRKCA
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Short nameAnti-PRKCA Thr637
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative namePRKCA(Thr637) Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetprotein kinase C, alpha, AAG6 and PKC-alpha and PKCA and PRKACA, PRKCA and IDBG-65194 and ENSG00000154229 and 5578, transferase activity, nuclei, Prkca and IDBG-213736 and ENSMUSG00000050965 and 18750, BT.62458 and IDBG-643753 and ENSBTAG00000001061 and 282001
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Gene info
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Identity
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Gene
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Long gene namePRKCA antisense RNA 1
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GenBank acession
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Locus
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Discovery year2014-10-10
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Entrez gene record
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RefSeq identity
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprotein kinase C alpha
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Synonyms gene
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Synonyms gene name
- protein kinase C, alpha
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Synonyms
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Locus
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Discovery year1991-08-02
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Entrez gene record
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Classification
- C2 domain containing protein kinases
- AGC family kinases
- MicroRNA protein coding host genes
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data