Rat Anti-Mouse CD80/B7-1-PE
-
Catalog number
GEN673447
-
Price
Please ask
-
Size
200ug
-
-
Also known as
CD80/B7-1
-
Other names
CD80/B7-1 transmembrane form; N/A; CD80/B7-1 transmembrane form; N/A; N/A
-
Category
Secondary Antibodies
-
Subcategory
Mnoclonal antibodies
-
Gene name
LOC554317; N/A; N/A; N/A
-
Gene name synonims
LOC554317; N/A; N/A; N/A
-
Other gene names
LOC554317; N/A; N/A; N/A
-
Clonality
Monoclonal
-
Immunoglobulin isotype
Rat IgG2a kappa
-
Clone
1G10
-
Host organism
Rat (Rattus norvegicus)
-
Species reactivity
Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
-
Specificity and cross reactivity
Mouse CD80 (B7-1), Mr 45-47 kDa CD80 (B7-1) is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed by dendritic cells, monocytes, and peritoneal macrophages. Expression of CD80 on B cells is upregulated after activation by various means including stimulation by LPS, IL- 4, and surface Ig receptor cross linking with peak expression occurring between 48 and 72 hours postactivation. ^1-4 The interaction of CD80/B7-1 with its ligands, CD28 and CD152/CTLA-4, provides a potent costimulatory signal for T cells activated through the CD3/T cell receptor complex.^5, 6 The monoclonal antibody 1G10 blocks binding of CTLA-4 to CD80, but it does not block stimulation of T cells by natural antigenpresenting cells. ^2, 7; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
-
Purification method
N/A
-
Form Appearance
R - phycoerythrin (R - PE) Conjugate
-
Concentration
N/A
-
Storage and shipping
The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL or 0.2 mg in 2.0 mL of PBS/NaN3 and a stabilizing agent. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. Do not freeze! The allophycocyanin (APC) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. Do not freeze! The Spectral Red (SPRD) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. Do not freeze! The low endotoxin, azide-free (LE/AF) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS. Aliquot and store at or below Store the antibody at -20 degrees Celsius.. Protect conjugated forms from light. Aliquot and freeze the low endotoxin, azide-free product the antibody should be stored at -20 degrees Celsius. immediately upon receipt. Each reagent is stable for the period shown on the bottle label if stored as directed.
-
Tested applications
Flow Cytometry; Immunoprecipitation
-
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
-
Latin name
Mus musculus, Rattus norvegicus
-
About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
-
Gene target
-
Gene symbol
CD80, ETV3, HHLA2, ERF, RNY4P2, LRRC23, PCDHGB7, NCR3LG1, CD274, CD86
-
Short name
Anti-Mouse CD80/B7-1-PE
-
Technique
anti-, Mouse, anti, antibody to, antibodies, mouses
-
Host
Rat
-
Label
PE
-
Species
Mouse, Mouses, Rats
-
Alternative name
Anti-Rat Anti-Mouse CD80/B7-1-PE
-
Alternative technique
murine, antibodies
-
Alternative to gene target
CD80 molecule, B7 and B7-1 and B7.1 and BB1 and CD28LG and CD28LG1 and LAB7, CD80 and IDBG-51287 and ENSG00000121594 and 941, coreceptor activity, Cell surfaces, Cd80 and IDBG-160288 and ENSMUSG00000075122 and 12519, BT.27986 and IDBG-632750 and ENSBTAG00000018059 and 407131
-
Gene info
-
Identity
-
Gene
-
Long gene name
CD80 molecule
-
Synonyms gene
-
Synonyms gene name
- CD80 antigen (CD28 antigen ligand 1, B7-1 antigen)
- CD80 molecule
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year
1993-12-14
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- B7 family
- CD molecules
- C2-set domain containing
- V-set domain containing
-
VEGA ID
Gene info
Gene info
-
Identity
-
Gene
-
Long gene name
HERV-H LTR-associating 2
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year
1999-09-07
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- C1-set domain containing
- V-set domain containing
- B7 family
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene name
ETS2 repressor factor
-
Synonyms gene name
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year
1998-07-17
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- ETS transcription factor family
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene name
RNY4 pseudogene 2
-
Synonyms gene name
- RNA, Y4 small cytoplasmic (associated with Ro protein) pseudogene 2
- RNA, Ro-associated Y4 pseudogene 2
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year
1993-08-25
-
Entrez gene record
-
RefSeq identity
Gene info
Gene info
Gene info
Gene info
-
Identity
-
Gene
-
Long gene name
CD274 molecule
-
Synonyms gene
-
Synonyms gene name
- programmed cell death 1 ligand 1
- CD274 antigen
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
2003-11-13
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Receptor ligands
- C2-set domain containing
- V-set domain containing
- B7 family
- CD molecules
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene name
CD86 molecule
-
Synonyms gene
-
Synonyms gene name
- CD86 antigen (CD28 antigen ligand 2, B7-2 antigen)
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year
1994-12-07
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- B7 family
- CD molecules
- V-set domain containing
-
VEGA ID
Product images
Similar products
