Cilostamide

• Catalog number
  2560-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  N-Cyclohexyl-N-methyl-4-(1,2-dihydro-2-oxo-6-quinolyloxy)butyramide
• Description
  A selective type III phosphodiesterase-3 (PDE3) inhibitor. Displays limited selectivity for PDE3A versus PDE3B (IC₅₀ = 27 and 50 nM). This inhibitory effect increases intracellular cAMP and inhibits platelet aggregation. Cilostamide also blocks PKB/Akt signaling pathway downstream via inhibition of Akt-activated PDE3B.
• CAS Number
  68550-75-4
• Structure Available
  Y
• Salt Form
  No
• Molecular Formula
  C₂₀H₂₆N₂O₃
• Molecular Weight
  342.44
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~30 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A selective type III phosphodiesterase-3 (PDE3) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  Gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD00673958
• PubChem CID
  2753
• PubChem CID Link
• SMILES
  CN(C1CCCCC1)C(=O)CCCOC2=CC3=C(C=C2)NC(=O)C=C3
• InChi
  InChI=1S/C20H26N2O3/c1-22(16-6-3-2-4-7-16)20(24)8-5-13-25-17-10-11-18-15(14-17)9-12-19(23)21-18/h9-12,14,16H,2-8,13H2,1H3,(H,21,23)
• InChi Key
  UIAYVIIHMORPSJ-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Cilostamide  
• Short name
  Cilostamide
• Alternative name
  Cilostamide

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