Bleomycin sulfate

• Catalog number
  2246-10
• Price
  Please ask
• Size
  10 mg

• Alternative_name
  Blenoxane, Bleo, Blexane
• Description
  An antitumor antibiotic isolated from Streptomyces verticillus. Radiomimetic DNA-cleaving agent that produces double and single DNA strand breaks through an oxygen-radical-dependent mechanism. Inhibits intracellular DNA replication. DNA alkylating agent. Inducer and regulator of apoptosis in a variety of cells. Inhibits tumor angiogenesis.
• CAS Number
  9041-93-4
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₅₅H₈₄N₁₇O₂₁S₃ · xH₂SO₄
• Molecular Weight
  1415.55. x98.08
• Cell Permeable
  No
• Purity
  ≥90% (A₂ +B₂)
• Solubilities
  H2O (10 mg/ml)
• Handling
  Protect from light and moisture
• Tag Line
  An antitumor antibiotic
• Storage Condition
  +4°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD00070310
• PubChem CID
  46930981
• PubChem CID Link
• SMILES
  CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O.OS(=O)(=O)[O-]
• InChi
  InChI=1S/C55H83N17O2InChI=1S3.H2O4S/c1-20-33(69-46(72-44(20)58)25(12-31(57)76)64-13-24(56)45(59)82)50(86)71-35(41(26-14-61-19-65-26)91-54-43(39(80)37(78)29(15-73)90-54)92-53-40(81)42(93-55(60)88)38(79)30(16-74)89-53)51(87)66-22(3)36(77)21(2)47(83)70-34(23(4)75)49(85)63-10-8-32-67-28(18-94-32)52-68-27(17-95-52)48(84)62-9-7-11-96(5)6;1-5(2,3)4/h14,17-19,21-25,29-30,34-43,53-54,64,73-75,77-81H,7-13,15-16,56H2,1-6H3,(H13-,57,58,59,60,61,62,63,65,66,69,70,71,72,76,82,83,84,85,86,87,88);(H2,1,2,3,4)/t21-,22+,23-,24-,25+,29-,30-,34-,35+,36-,37+,38-,39-,40+,41?,42+,43-,53-,54-;/m1./s1
• InChi Key
  WUIABRMSWOKTOF-PATWWPTKSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Bleomycin   sulfate  
• Short name
  Bleomycin sulfate
• Alternative name
  Bleomycin sulfate

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