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Alternative_name
(2-(2,2,6,6-Tetramethylpiperidin-1-oxyl-4-ylamino)-2-oxoethyl)triphenylphosphonium chloride, Mito-TEMPO
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Description
Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic that possesses superoxide and alkyl radical scavenging properties. Mitochondrial targeting of superoxide scavenging using mito-TEMPO has been examined for potential therapeutic benefit to a variety of mitochondrondrial dysfunctions arising from excessive reactive oxygen species.
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Structure Available
Yes
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Molecular Formula
C₂₉H₃₅ClN₂O₂P · H₂O
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Molecular Weight
528.04
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Cell Permeable
Yes
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Purity
≥95%
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Solubilities
H₂O (~10 mg/ml)
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Handling
Protect from air and light
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Tag Line
A mitochondria-targeted superoxide dismutase mimetic and antioxidant
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Storage Condition
-20°C
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Shipping Condition
Gel pack
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Shelf Life
36 months
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SMILES
O=C(NC1CC(C)(C)N([O-])C(C)(C)C1)C[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4.[H]O[H].[Cl-]
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InChi
InChI=1S/C29H35N2O2P.ClH.H2O/c1-28(2)20-23(21-29(3,4)31(28)33)30-27(32)22-34(24-14-8-5-9-15-24,25-16-10-6-11-17-25)26-18-12-7-13-19-26;;/h5-19,23H,20-22H2,1-4H3,(H,30,32);1H;1H2/p-1
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InChi Key
AFQGOTBLJZNJMW-UHFFFAOYSA-M
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MSDS Available
Yes