anti-MAPK1 Antibody

• Catalog number
  48-785
• Price
  Please ask
• Size
  0.05 mL

• Gene info
  ERK2, a MAPK type protein kinase, is a member of the Ras MAPK pathway. This pathway modulates the activity of transcription factors, structural proteins and other protein kinases, leading to biological responses such as cell proliferation and differentiation. Inactive ERK2 associates with MAPK/ERK kinases (MEK) 1 and 2 in the cytosol. Upon stimulation, MEK1/2 phosphorylates and activates ERK2 causing dissociation of the MEK/ERK complex. A portion of the activated ERK2 pool forms dimers and translocates to the nucleus to activate nuclear proteins, such as ELK-1 and MSK1. Cytosolic ERK 2 acts on a different set of substrates, including MNK1/2 and MAPKAP-K1.
• Gene names
  MAPK1, ERK, ERK-2, ERK2, MAP kinase 1, MAPK 2, MAPK2, MAP kinase isoform p42, MAPK 1, p41mapk, PRKM2, MAP kinase 2, p41, p42-MAPK, PRKM1, ERT1, p38, p40, p42MAPK, Protein tyrosine kinase ERK2
• Antibodie s label
  unlabelled serum
• Purity
  Affinity Chromatography
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  MAPK1 antibody was made against a peptide mapping to the carboxy terminus of MAPK1 (Rat).
• Immuno application
  Western Blot, immuno-histo-chemistry, immuno precipitation
• Antibody advice
  MAPK1 antibody can be used in immunohistochemistry starting at 10 ug/mL, immunoprecipitation, and flow cytometry.
• Suspention pH azide
  Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 50% glycerol, 0.1% gelatin.
• Keep at
  Store MAPK1 antibody at 4 grades C or -20 grades C. As with all antibodies avoid freeze/thaw cycles.
• Works with
  Human, Mouse, Rat
• Omim nr
  119554
• Ncbi nr
  P28482
• Vial with antibody
  in solution
• NCBI GENE nr
  5594
• GENE symbol
  MAPK1
• Antigene name
  mitogen-activated protein kinase 1
• Source
  Homo sapiens
• Protein nr
  P28482
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MAPK1  
• Gene symbol
  MAPK1
• Short name
  anti-MAPK1 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toMAPK1 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  mitogen-activated protein kinase 1, ERK and ERK-2 and ERK2 and ERT1 and MAPK2 and p38 and p40 and p41 and p41mapk and p42-MAPK and P42MAPK and PRKM1 and PRKM2, MAPK1 and IDBG-2147 and ENSG00000100030 and 5594, transferase activity, nuclei, Mapk1 and IDBG-137672 and ENSMUSG00000063358 and 26413, MAPK1 and IDBG-637539 and ENSBTAG00000010312 and 327672

Gene info

• Identity
  HGNC:6871
• Gene
  MAPK1
• Long gene name
  mitogen-activated protein kinase 1
• Synonyms gene
  • PRKM2
  • PRKM1
• Synonyms
  • ERK
  • ERK2
  • p41mapk
  • MAPK2
• GenBank acession
  • M84489
• Locus
  22q11.22
• Discovery year
  1993-11-05
• Entrez gene record
  5594
• Classification
  • Mitogen-activated protein kinases
• VEGA ID
  OTTHUMG00000030508
• Locus Specific Databases
  • LRG_786

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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