MOUSE Anti-MOUSE CD282 Antibody
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Catalog number
GEN219737
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Price
Please ask
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Size
0.025 miligrams
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Also known as
CD282
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Other names
toll-like receptor 2; Toll-like receptor 2; toll-like receptor 2; toll-like receptor 2; N/A
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
CD282
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Gene name synonims
N/A
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Other gene names
Tlr2; Tlr2; Ly105; N/A
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1
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Clone
T2.5
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Host organism
Mouse (Mus musculus)
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Species reactivity
Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
CD282 This item recognises CD282, also known as Toll-like receptor 2 (TLR2). It is expressed on smooth muscle, lung, spleen, thymus, brain and adipose tissue and plays a role in pathogen recognition and activation of the innate immune response to pathogens. Specifically it interacts with LY96 to mediate the immune response to bacterial lipoproteins and other microbial cell wall components. It activates NF-kappa-B, via MyD88 and TRAF6, leading to cytokine secretion and the inflammatory response. It may also promote apoptosis in response to lipoproteins. Clone T2.5 has been reported to inhibit CD282-dependent cell activation in vitro and in vivo. ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
N/A
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Form Appearance
Purified (Purified IgG - liquid)
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Concentration
IgG concentration 500ug/1000ul
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Storage and shipping
Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
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Tested applications
Immunoprecipitation (IP), Immunohistology - Frozen (IHC), Flow Cytometry (FACS)
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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French translation
anticorps
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Gene target
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Gene symbol
TLR2
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Short name
MOUSE Anti-MOUSE CD282 Antibody
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Technique
Antibody, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, mouses
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Host
mouse
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Species
Mouse, Mouses
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Alternative name
Anti-MOUSE ANTI MOUSE CD282
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Alternative technique
antibodies, murine
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Gene info
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Identity
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Gene
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Long gene name
toll like receptor 2
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Synonyms gene name
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Synonyms
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GenBank acession
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Locus
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Discovery year
1998-06-25
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Entrez gene record
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Pubmed identfication
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Classification
- Toll like receptors
- CD molecules
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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