Latrunculin A

  • Catalog number
    2181-100
  • Price
    Please ask
  • Size
    100 ug
  • Alternative_name
    LAT-A; NSC 613011
  • Description
    A cell-permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Depolymerizes actin filaments (F-actin) and acts as a phagocytosis inhibitor. Anticancer compound. Suppresses hypoxia-induced HIF-1 activation in tumor cells. Inhibits tumor cell invasion.
  • CAS Number
    76343-93-6
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₂H₃₁NO₅S
  • Molecular Weight
    421.55
  • Cell Permeable
    Yes
  • Purity
    ≥96% by HPLC
  • Solubilities
    DMSO or EtOH
  • Handling
    Protect from air and light
  • Tag Line
    Actin polymerization inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24months
  • MDL Number
    MFCD00272613
  • PubChem CID
    6437378
  • SMILES
    CC1CCC2CC(CC(O2)(C3CSC(=O)N3)O)OC(=O)C=C(CCC=CC=C1)C
  • InChi
    InChI=1S/C22H31NO5S/c1-15-7-5-3-4-6-8-16(2)11-20(24)27-18-12-17(10-9-15)28-22(26,13-18)19-14-29-21(25)23-19/h3-5,7,11,15,17-19,26H,6,8-10,12-14H2,1-2H3,(H,23,25)/b4-3-,7-5+,16-11+/t15-,17-,18-,19+,22-/m1/s1
  • InChi Key
    DDVBPZROPPMBLW-VREWCFMQSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Latrunculin A
  • Alternative name
    Latrunculin A
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