Latrunculin A
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Catalog number2181-100
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PricePlease ask
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Size100 ug
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Alternative_nameLAT-A; NSC 613011
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DescriptionA cell-permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Depolymerizes actin filaments (F-actin) and acts as a phagocytosis inhibitor. Anticancer compound. Suppresses hypoxia-induced HIF-1 activation in tumor cells. Inhibits tumor cell invasion.
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CAS Number76343-93-6
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₂H₃₁NO₅S
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Molecular Weight421.55
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Cell PermeableYes
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Purity≥96% by HPLC
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SolubilitiesDMSO or EtOH
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HandlingProtect from air and light
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Tag LineActin polymerization inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24months
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MDL NumberMFCD00272613
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PubChem CID6437378
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SMILESCC1CCC2CC(CC(O2)(C3CSC(=O)N3)O)OC(=O)C=C(CCC=CC=C1)C
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InChiInChI=1S/C22H31NO5S/c1-15-7-5-3-4-6-8-16(2)11-20(24)27-18-12-17(10-9-15)28-22(26,13-18)19-14-29-21(25)23-19/h3-5,7,11,15,17-19,26H,6,8-10,12-14H2,1-2H3,(H,23,25)/b4-3-,7-5+,16-11+/t15-,17-,18-,19+,22-/m1/s1
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InChi KeyDDVBPZROPPMBLW-VREWCFMQSA-N
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MSDS AvailableYes
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Gene target
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Short nameLatrunculin A
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Alternative nameLatrunculin A
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