anti- MAPKBP1 antibody

• Catalog number
  FNab05000
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  MAP kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. MAPKBP-1 (mitogen-activated protein kinase binding protein 1), also known as JNKBP-1, is a 1, 514 amino acid protein that contains twelve WD repeats. Induced by TRAF2 (TNF receptor-associated factor 2) and Tak1 (TGF-β-activated kinase 1), MAPKBP-1 is thought to act an adaptor protein for NFκB (nuclear factor κ-B) activation. MAPKBP-1 interacts with JNK3 and may promote TRAF2 polyubiquitination. MAPKBP-1 exists as six alternatively spliced variants and is encoded by a gene located on human chromosome 15. Human chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.
• Immunogen
  mitogen-activated protein kinase binding protein 1
• Synonyms
  JNKBP1, KIAA0596
• Calculated MW
  165 kDa
• Uniprot ID
  O60336
• Specificity
  Human, Mouse, Rat
• Tested Application
  ELISA, WB, IHC
• Recommended dilution
  WB: 1:200 - 1:500; IHC: 1:50 - 1:100
• Image1
  Immunohistochemistry of paraffin-embedded human pancreas using FNab05000(MAPKBP1 antibody) at dilution of 1:100
• Image4
  mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab05000(MAPKBP1 antibody) at dilution of 1:300
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MAPKBP1  
• Gene symbol
  MAPKBP1
• Short name
  anti- MAPKBP1 antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- MAPKBP1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:29536
• Gene
  MAPKBP1
• Long gene name
  mitogen-activated protein kinase binding protein 1
• Synonyms gene name
  • mitogen activated protein kinase binding protein 1
• Synonyms
  • KIAA0596
  • NPHP20
• GenBank acession
  • AB011168
• Locus
  15q15.1
• Discovery year
  2005-07-21
• Entrez gene record
  23005
• Pubmed identfication
  • 9628581
  • 10471813
• RefSeq identity
  • NM_014994
• Classification
  • WD repeat domain containing
• VEGA ID
  OTTHUMG00000160227

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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