Dalcetrapib
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Catalog number2419-5
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PricePlease ask
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Size5 mg
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Alternative_nameS-2-(1-(2-ethylbutyl)cyclohexanecarboxamido)phenyl 2-methylpropanethioate; JTT-705; RO4607381
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DescriptionDalcetrapib is a potent CETP modulator. It is a thioester pro-drug that is rapidly hydrolyzed to generate a pharmacologically active thiol. Dalcetrapib modulates cholesteryl ester transfer protein (CETP) activity to raise high-density lipoprotein cholesterol (HDL-C). It achieves 50% inhibition of CETP activity in human plasma at a concentration of 9 μM.
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CAS Number211513-37-0
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₃H₃₅NO₂S
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Molecular Weight389.59
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Cell PermeableYes
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Purity≥98%
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SolubilitiesDMSO (>50 mg/ml) or EtOH (>50 mg/ml)
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HandlingProtect from light and air
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Tag LineA CETP inhibitor
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Storage Condition-20 ̊C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID6918540
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SMILESCCC(CC)CC1(CCCCC1)C(=O)NC2=CC=CC=C2SC(=O)C(C)C
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InChiInChI=1S/C23H35NO2S/c1-5-18(6-2)16-23(14-10-7-11-15-23)22(26)24-19-12-8-9-13-20(19)27-21(25)17(3)4/h8-9,12-13,17-18H,5-7,10-11,14-16H2,1-4H3,(H,24,26)
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InChi KeyYZQLWPMZQVHJED-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameDalcetrapib
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Alternative nameDalcetrapib
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