Collagen IV Antibody, ALEXA FLUOR 555
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Catalog numberbs-0806R-A555
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PricePlease ask
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Size100ul
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Long nameCollagen IV Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
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Also known asAnti-Collagen IV PAb ALEXA FLUOR 555
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 555
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenCollagen IV
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SpecificityThis is a highly specific antibody against Collagen IV.
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ModificationUnmodified
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Modification SiteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range1430-1480/1669
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Subcellular locationSecreted
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SourceKLH conjugated synthetic peptide derived from mouse Collagen alpha-1(IV) chain
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Gene ID Number12826
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Swiss ProtP02463
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigenType IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin (By similarity).
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission553nm/568nm
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SynonymsBru; Raw; Svc; Col4a-1; Del(8)44H; Collagen alpha-1(IV) chain; Col4a1
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PropertiesFor facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor, ALEXA FLUOR 555
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GeneCollagen Types in bones and muscles can be hydrolyzed and used in human grafts. ( Type II )
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French translationanticorps
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Gene target
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Gene symbolCOL4A6, COL4A5, COL4A1
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Short nameAnti-Collagen IV
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 555
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Alternative nameCollagen IV Polyclonal Antibody, ALEXA FLUOR 555
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namecollagen type IV alpha 6 chain
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Synonyms gene name
- collagen, type IV, alpha 6
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GenBank acession
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Locus
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Discovery year1993-10-01
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Entrez gene record
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Pubmed identfication
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Classification
- Collagens
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namecollagen type IV alpha 5 chain
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Synonyms gene
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Synonyms gene name
- Alport syndrome
- collagen, type IV, alpha 5
- collagen type IV alpha 5
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Classification
- Collagens
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namecollagen type IV alpha 1 chain
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Synonyms gene name
- collagen, type IV, alpha 1
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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Classification
- Collagens
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data