TDP1 Antibody (Clone AT1F2)

• Catalog number
  6698-50
• Price
  Please ask
• Size
  50 μg

• Antibody Target
  TDP1
• Target Alternative Name
  Tyrosyl-DNA phosphodiesterase 1, TDP1 protein, TDP1.
• Antibody Type
  Monoclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Recombinant human TDP1 (1-298aa) purified from E. Coli. Anti-human TDP1 mAb, clone AT1F2, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TDP1 protein.
• Accession
  Q9NUW8
• Gene Id
  55775
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  1 mg/ml
• Formulation
  Supplied in PBS with 0.1% sodium azide.
• Purification
  Protein-G affinity purified
• Application
  Western Blot, ELISA
• Positive Control
  Western blot: MCF7 Cell lysate
• Application And Usages
  Western blot: ~1:1000 - 2000, ELISA.
• Description
  Tyrosyl-DNA phosphodiesterase (TDP1) is a DNA repair enzyme that catalyzes the hydrolysis of a phophodiester bond between a tyrosine residue and a DNA 3' phosphate. This protein is a member of the phospholipase D (PLD) superfamily and contains two PLD phosphodiesterase domains. Mutations in TDP1 are associated with the disease spino-cerebellar ataxia with axonal neuropathy (SCAN1) by interfering with DNA transcription or by inducting apoptosis in postmitotic neurons.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TDP1   AT1F2  
• Gene symbol
  TDP1
• Short name
  TDP1 Antibody (Clone AT1F2)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Mouse IgG1k
• Alternative name
  TDP1 (antibody to-) (clonality AT1F2)
• Alternative technique
  antibodies
• Clone name
  AT1F2

Gene info

• Identity
  HGNC:18884
• Gene
  TDP1
• Long gene name
  tyrosyl-DNA phosphodiesterase 1
• Synonyms
  • FLJ11090
  • SCAN1
• GenBank acession
  • AF182002
• Locus
  14q32.11
• Discovery year
  2002-07-13
• Entrez gene record
  55775
• Pubmed identfication
  • 11839309
  • 12244316
• RefSeq identity
  • NM_018319
• VEGA ID
  OTTHUMG00000171016

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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