Anti-APC1 (Ser377) (Polyclonal), ALEXA Fluor 594

• Catalog number
  GENTObs-5174R-A594
• Price
  Please ask
• Size
  100 microliters

• Type
  Conjugated Primary Antibody
• Conjugated with
  ALEXA FLUOR® 594
• Host organism
  Rabbit (Oryctolagus cuniculus)
• Target Protein Peptide
  APC1 Ser377
• Specificity
  This antibody reacts specifically with APC1 (Ser377)
• Modification
  Phosphorylation
• Modification site
  Ser377
• Clonality
  Polyclonal Antibody
• Clone
  Polyclonal Antibodies
• Concentration
  1ug per 1ul
• Subcellular locations
  N/A
• Antigen Source
  KLH conjugated synthetic phosphopeptide derived from human ANAPC1 around the phosphorylation site of Ser377
• Gene ID
  64682
• Swiss Prot
  N/A
• Applications
  IF(IHC-P)
• Applications with corresponding dilutions
  IF(IHC-P)(1:50-200)
• Cross reactive species
  Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
• Cross Reactive Species details
  No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
• Background information
  This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011].
• Purification method
  Purified by Protein A.
• Storage
  Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
• Excitation emission
  590nm/617nm
• Synonyms
  Apc1 phospho S377; p-Apc1 phospho S377; ANAPC1Ser377; ANAPC 1; ANAPC1; Anaphase promoting complex subunit 1; anaphase-promoting complex 1 meiotic checkpoint regulator; Anaphase-promoting complex subunit 1; Apc 1; APC1; APC1_HUMAN; Cyclosome subunit 1; MCPR; Meiotic checkpoint regulator; Mitotic checkpoint regulator; Protein Tsg 24; Protein Tsg24; Testis-specic gene 24 protein; TSG 24; TSG24.
• Also known as
  APC1 (Ser377) Polyclonal Antibody
• Other name
  Anti-APC1 (Ser377) Polyclonal
• Advisory
  Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Properties
  For facs or microscopy Alexa 1 conjugate.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

• Gene target
  APC1   Ser377  
• Gene symbol
  SLC25A24, ANAPC1
• Short name
  Anti-APC1 (Ser377)
• Technique
  Polyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  APC1 (Ser377) Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:20662
• Gene
  SLC25A24
• Long gene name
  solute carrier family 25 member 24
• Synonyms gene name
  • solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
• Synonyms
  • DKFZp586G0123
  • APC1
• GenBank acession
  • AJ619961
• Locus
  1p13.3
• Discovery year
  2004-05-05
• Entrez gene record
  29957
• Pubmed identfication
  • 15123600
• RefSeq identity
  • NM_013386
• Classification
  • Solute carriers
  • EF-hand domain containing
• VEGA ID
  OTTHUMG00000011013

Gene info

• Identity
  HGNC:19988
• Gene
  ANAPC1
• Long gene name
  anaphase promoting complex subunit 1
• Synonyms
  • MCPR
  • TSG24
  • APC1
• GenBank acession
  • AJ278357
• Locus
  2q13
• Discovery year
  2004-01-13
• Entrez gene record
  64682
• Pubmed identfication
  • 11179667
• RefSeq identity
  • NM_022662
• Classification
  • Anaphase promoting complex
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000131277

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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