Kobe2602

• Catalog number
  B1710-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  Kobe2602; kobe 2602; kobe-2602; Kobe 2602; Kobe-2602; 2-(2,6-dinitro-4-(trifluoromethyl)phenyl)-N-(4-fluorophenyl)hydrazinecarbothioamide; 1-[2,6-dinitro-4-(trifluoromethyl)anilino]-3-(4-fluorophenyl)thiourea
• Description
  Kobe2602 is a novel and effective small-molecule compound inhibiting Ras–Raf interaction by SBDD; exhibits potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 149 ± 55 μM.
• CAS Number
  454453-49-7
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₄H₉F₄N₅O₄S
• Molecular Weight
  419.31
• Cell Permeable
  Yes
• Purity
  >98%
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A Ras inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  3827738
• PubChem CID Link
• SMILES
  C1=CC(=CC=C1NC(=S)NNC2=C(C=C(C=C2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])F
• InChi
  InChI=1S/C14H9F4N5O4S/c15-8-1-3-9(4-2-8)19-13(28)21-20-12-10(22(24)25)5-7(14(16,17)18)6-11(12)23(26)27/h1-6,20H,(H2,19,21,28)
• InChi Key
  NNPBSITXCGPXJC-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Kobe2602  
• Short name
  Kobe2602
• Alternative name
  Kobe2602

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