IOX2

• Catalog number
  9451-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  N-[[1,2-Dihydro-4-hydroxy-2-oxo-1-(phenylmethyl)-3-quinolinyl]carbonyl]glycine
• Description
  IOX-2 is a potent, cell-permeable and selective inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) (IC₅₀ = 21 nM). It displays over 100-fold selectivity for PHD2 over factor inhibiting HIF-1 (FIH-1) and histone demethylases JMJD2A, JMJD2C, JMJD2E and JMJD3.
• CAS Number
  931398-72-0
• Structure Available
  Yes
• Molecular Formula
  C₁₉H₁₆N₂O₅
• Molecular Weight
  352.34
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>30 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A selective inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2)
• Storage Condition
  -20°C
• Shipping Condition
  Gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD22580424
• PubChem CID
  54685215
• PubChem CID Link
• SMILES
  C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=C(C2=O)C(=O)NCC(=O)O)O
• InChi
  InChI=1S/C19H16N2O5/c22-15(23)10-20-18(25)16-17(24)13-8-4-5-9-14(13)21(19(16)26)11-12-6-2-1-3-7-12/h1-9,24H,10-11H2,(H,20,25)(H,22,23)
• InChi Key
  CAOSCCRYLYQBES-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  IOX2  
• Short name
  IOX2
• Alternative name
  IOX2

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