Recombinant Mouse Fc γ RI/FCGR1A/CD64 Protein(C-6His) 50µg
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Catalog number
PKSM041015-50µg
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Price
Please ask
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Size
50µg
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Activity
NA
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Synonym
High affinity immunoglobulin gamma Fc receptor I; IgG Fc receptor I; Fc-gamma RI; FcRI; CD64
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Sequence
Glu25-Pro297
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Fusion tag
C-6His
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Accession
P26151
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Expressed Host
Human Cells
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Shipping
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
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Purity
＞95% as determined by reducing SDS-PAGE.
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Stability and Storage
Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
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Mol Mass
31.5 kDa
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AP Mol Mass
40-60 kDa
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Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
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Background
CD64, also known as Fc-gamma receptor 1 (FcγRI), is a type of integral membrane glycoprotein that binds monomeric IgG-type antibodies with high affinity. After binding IgG, CD64 interacts with an accessory chain known as the common γ chain (γ chain), which possesses an ITAM motif that is necessary for triggering cellular activation. CD64 is composed of a signal peptide, three extracellular immunoglobulin domains of the C2-type used to bind antibody, a hydrophobic transmembrane domain, and a short cytoplasmic tail. CD64 mediates endocytosis, phagocytosis, antibody-dependent cellular cytotoxicity, cytokine release, and superoxide production. It is normally expressed on the surfaces of monocytes and macrophages.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
FCGR1A
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Short name
Recombinant Mouse Fc γ RI/FCGR1A/CD64 Protein(C-6His) 50µg
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Technique
Recombinant, Mouse, FC, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Host
mouse
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Species
Mouse, Mouses
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Alternative name
Rec. Mouse fragment c γ RI/fragment c fragment on Immunoglobulin G, high affinity Ia, receptor (CD64)/CD64 Protein(C-6His) 50µg
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Alternative technique
rec, murine
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Alternative to gene target
Fc fragment of IgG, high affinity Ia, receptor (CD64), CD64 and CD64A and FCRI and IGFR1, FCGR1A and IDBG-101961 and ENSG00000150337 and 2209, IgG binding, Plasma membranes
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Gene info
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Identity
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Gene
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Long gene name
Fc gamma receptor Ia
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Synonyms gene name
- Fc fragment of IgG, high affinity Ia, receptor for (CD64)
- Fc fragment of IgG, high affinity Ia, receptor (CD64)
- Fc fragment of IgG receptor Ia
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1992-12-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Immunoglobulin like domain containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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