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Sulfo LC SPDP for cell activation

Sulfo LC SPDP for cell activation is available 2 times from Biovision labs

2325-50 | Sulfo-LC-SPDP for cell activation size: 50 mg | 494.69 USD

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2325-250 | Sulfo-LC-SPDP for cell activation size: 250 mg | 1,777.92 USD

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Other name Sulfosuccinimidyl 6-(3'-[2-pyridyldithio]-propionamido)hexanoate
Supplied with N/A
Description KEY FEATURES: • Sulfo-LC-SPDP releases a byproduct, pyridine-2-thione after reacting with free sulfhydryl groups. By measuring the release of this byproduct at 343 nm, the reaction can be easily followed • Amine-reactive; the "long chain" Sulfo-LC-SPDP crosslinking reagent has a 15.7 Å spacer arm • More water-soluble than the corresponding LC-SPDP • Membrane-impermeable which enables crosslinking on cell surface • The cleavable spacer arm enables separation of cross-linked products APPLICATIONS: • Reversible crosslinking of proteins • N-hydroxysulfosuccinimide (Sulfo-NHS) ester that reacts with primary amines, as found in lysine side chains • Sulfo-LC-SPDP crosslinking molecule pyridinyldisulfide reacts with sulhydryls to yield a reversible disulfide bond.
Category Biochemicals
Molecular formula C₁₈H₂₂O₈N₃S₃Na
Is it cell-permeable? No
Molecular weight 527.57
Storage condition -20 ̊C
Shipping condition Gel Pack
Purification ≥90% by NMR
Peptide sequence N/A
Is this a salt? No
CAS number N/A
Storage instructions Protect from moisture
Maximum time for storage 36 months
Physical appearance White to Off-white Solid
Reconstitute instructions H₂O (~ 6 mg/ml)
Additional description For cells, cell lines and tissues in culture till half confluency.
Short name Sulfo-LC-SPDP for activation
Technique activation
Alternative name Sulfo-LC-SPDP to measure cellular activation
Tissue cell
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