Human CellExp™ LTBR /TNFRSF3, Human recombinant

• Catalog number
  P1111-10
• Price
  Please ask
• Size
  10 ug

• Synonyms
  LTBR, D12S370, TNFCR, TNFR3, TNFRSF3, TNFRIII
• Alternative_names
  LTBR, D12S370, TNFCR, TNFR3, TNFRSF3, TNFRIII
• Description
  Promotes apoptosis via TRAF3 and TRAF5
• Recombinant
  Yes
• Source
  HEK293 cells
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 1 EU/ug
• Molecular Weight
  48.4 kDa
• Storage Temp
  -20°C
• Shipping
  Gel pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Generally Mannitol or Trehalose is added as a protectant before lyophilization.
• Reconstitution Instructions
  Reconstitute with 100 µl sterile water.
• Background Information
  Lymphotoxin-beta receptor (LTBR) is also known as Tumor necrosis factor receptor superfamily member 3 (TNFRSF3), Tumor necrosis factor receptor type III (TNF-RIII), which is a single-pass type I membrane protein containing four TNFR-Cys repeat regions. Except for interacting with HCV core protein, LTBR can not only associate with itself, but also can associate with TRAF3, TRAF4 and TRAF5. As the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT, LTBR promotes apoptosis via TRAF3 and TRAF5. Furthermore, LTBR may play a role in the development of lymphoid organs.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CellExp™   LTBR   TNFRSF3  
• Gene symbol
  LTBR
• Short name
  CellExp™ LTBR /TNFRSF3, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Humans
• Alternative name
  H. sapiens CellExp™ lymphotoxin beta receptor (TNFR superfamily, member 3) /TNFRSF3, H. sapiens Rec.
• Alternative technique
  rec
• Alternative to gene target
  lymphotoxin beta receptor (TNFR superfamily, member 3), CD18 and D12S370 and LT-BETA-R and TNF-R-III and TNFCR and TNFR-RP and TNFR2-RP and TNFR3 and TNFRSF3, LTBR and IDBG-13973 and ENSG00000111321 and 102724071,4055, identical protein binding, Plasma membranes, Ltbr and IDBG-189788 and ENSMUSG00000030339 and 17000, LTBR and IDBG-640501 and ENSBTAG00000015312 and 504653

Gene info

• Identity
  HGNC:6718
• Gene
  LTBR
• Long gene name
  lymphotoxin beta receptor
• Synonyms gene
  • D12S370
• Synonyms
  • TNFCR
  • TNFR-RP
  • TNFR2-RP
  • TNF-R-III
  • TNFRSF3
• Synonyms name
  • TNFR superfamily, member 3
• GenBank acession
  • L04270
• Locus
  12p13.31
• Discovery year
  1996-03-12
• Entrez gene record
  4055
• Pubmed identfication
  • 8171323
  • 8486360
• Classification
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000168356

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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