CD171/ NCAM-L1 Antibody

• Catalog number
  GEN438259
• Price
  Please ask
• Size
  100ug

• Also known as
  CD171
• Other names
  neural cell adhesion molecule L1 isoform 1; Neural cell adhesion molecule L1; neural cell adhesion molecule L1; antigen identified by monoclonal antibody R1; L1 cell adhesion molecule; CD_antigen: CD171
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  L1CAM
• Gene name synonims
  N/A
• Other gene names
  L1CAM; L1CAM; S10; HSAS; MASA; MIC5; SPG1; CAML1; CD171; HSAS1; N-CAML1; NCAM-L1; N-CAM-L1; CAML1; MIC5; N-CAM-L1; NCAM-L1
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1, kappa
• Clone
  UJ127
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes a cell surface protein of 220-240kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  N/A
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
• Tested applications
  ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB), Immunohistology (IH)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CD171   NCAM-L1  
• Gene symbol
  L1CAM, NCAM1, MTA2, MICALL1, IGKV1-16, ZBTB4, UCHL1, COLEC10, FAM71F1, KLK4
• Short name
  CD171/ NCAM-L1 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Anti-CD171/ NCAM-L1
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6470
• Gene
  L1CAM
• Long gene name
  L1 cell adhesion molecule
• Synonyms gene
  • HSAS1
  • SPG1
  • HSAS
  • MASA
  • MIC5
  • S10
• Synonyms gene name
  • antigen identified by monoclonal antibody R1
• Synonyms
  • CD171
  • NCAM-L1
  • CAML1
• Synonyms name
  • neural cell adhesion molecule L1
• GenBank acession
  • M74387
• Locus
  Xq28
• Discovery year
  1989-06-30
• Entrez gene record
  3897
• RefSeq identity
  • NM_024003
• Classification
  • Ig-like cell adhesion molecule family
  • I-set domain containing
  • Fibronectin type III domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000024221
• Locus Specific Databases
  • Global Variome shared LOVD
  • NGRL, Manchester LOVD
  • Global Variome shared LOVD
  • LRG_14

Gene info

• Identity
  HGNC:7656
• Gene
  NCAM1
• Long gene name
  neural cell adhesion molecule 1
• Synonyms
  • NCAM
  • CD56
• Locus
  11q23.2
• Discovery year
  2001-06-22
• Entrez gene record
  4684
• RefSeq identity
  • NM_000615
• Classification
  • Fibronectin type III domain containing
  • CD molecules
  • Ig-like cell adhesion molecule family
  • I-set domain containing
• VEGA ID
  OTTHUMG00000167196

Gene info

• Identity
  HGNC:7411
• Gene
  MTA2
• Long gene name
  metastasis associated 1 family member 2
• Synonyms gene
  • MTA1L1
• Synonyms gene name
  • metastasis associated gene family, member 2
• Synonyms
  • MTA1-L1
• GenBank acession
  • AB016591
• Locus
  11q12.3
• Discovery year
  1999-05-17
• Entrez gene record
  9219
• Pubmed identfication
  • 9929979
• RefSeq identity
  • NM_004739
• Classification
  • GATA zinc finger domain containing
  • NuRD complex subunits
  • Myb/SANT domain containing
• VEGA ID
  OTTHUMG00000167684

Gene info

• Identity
  HGNC:29804
• Gene
  MICALL1
• Long gene name
  MICAL like 1
• Synonyms gene name
  • MICAL-like 1
• Synonyms
  • MIRAB13
  • KIAA1668
  • MICAL-L1
• Synonyms name
  • molecule interacting with Rab13
• GenBank acession
  • BK000466
• Locus
  22q13.1
• Discovery year
  2006-11-24
• Entrez gene record
  85377
• Pubmed identfication
  • 11258795
  • 12110185
• RefSeq identity
  • NM_033386
• Classification
  • LIM domain containing
• VEGA ID
  OTTHUMG00000150670

Gene info

• Identity
  HGNC:5732
• Gene
  IGKV1-16
• Long gene name
  immunoglobulin kappa variable 1-16
• Synonyms
  • IGKV116
  • L1
• GenBank acession
  • J00248
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28938
• RefSeq identity
  • NG_000834
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151649

Gene info

• Identity
  HGNC:23847
• Gene
  ZBTB4
• Long gene name
  zinc finger and BTB domain containing 4
• Synonyms
  • KIAA1538
  • KAISO-L1
  • ZNF903
• GenBank acession
  • AB040971
• Locus
  17p13.1
• Discovery year
  2003-12-15
• Entrez gene record
  57659
• Pubmed identfication
  • 16354688
  • 25499219
• RefSeq identity
  • NM_020899
• Classification
  • BTB domain containing
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000108137

Gene info

• Identity
  HGNC:12513
• Gene
  UCHL1
• Long gene name
  ubiquitin C-terminal hydrolase L1
• Synonyms gene
  • PARK5
• Synonyms gene name
  • ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
• Synonyms
  • PGP9.5
  • Uch-L1
• Synonyms name
  • ubiquitin thiolesterase
• GenBank acession
  • BC000332
• Locus
  4p13
• Discovery year
  1991-07-15
• Entrez gene record
  7345
• Pubmed identfication
  • 1840236
• RefSeq identity
  • NM_004181
• Classification
  • Ubiquitin C-terminal hydrolases
• VEGA ID
  OTTHUMG00000099377

Gene info

• Identity
  HGNC:2220
• Gene
  COLEC10
• Long gene name
  collectin subfamily member 10
• Synonyms gene name
  • collectin sub-family member 10 (C-type lectin)
• Synonyms
  • CL-L1
  • CL-10
• GenBank acession
  • AB002631
• Locus
  8q24.12
• Discovery year
  2000-04-11
• Entrez gene record
  10584
• Pubmed identfication
  • 10224141
• Classification
  • Collectins
  • C-type lectin domain containing
  • Complement system activation components
• VEGA ID
  OTTHUMG00000164971

Gene info

• Identity
  HGNC:30704
• Gene
  FAM71F1
• Long gene name
  family with sequence similarity 71 member F1
• Synonyms gene
  • FAM137A
• Synonyms gene name
  • family with sequence similarity 137, member A
  • family with sequence similarity 71, member F1
• Synonyms
  • NYD-SP18
  • GARI-L1
• Synonyms name
  • Golgi-associated RAB2B interactor like 1
• GenBank acession
  • AF367470
• Locus
  7q32.1
• Discovery year
  2007-07-24
• Entrez gene record
  84691
• Pubmed identfication
  • 12477932
  • 34714330
• RefSeq identity
  • NM_032599
• VEGA ID
  OTTHUMG00000158276

Gene info

• Identity
  HGNC:6365
• Gene
  KLK4
• Long gene name
  kallikrein related peptidase 4
• Synonyms gene
  • PRSS17
• Synonyms gene name
  • kallikrein 4 (prostase, enamel matrix, prostate)
• Synonyms
  • EMSP
  • EMSP1
  • PSTS
  • KLK-L1
• Synonyms name
  • enamel matrix serine proteinase 1
• GenBank acession
  • AF113141
• Locus
  19q13.41
• Discovery year
  1999-04-29
• Entrez gene record
  9622
• Pubmed identfication
  • 10077646
  • 10438493
  • 16800724
  • 10863090
  • 9465170
• RefSeq identity
  • NM_004917
• Classification
  • Kallikreins
  • Serine proteases
• VEGA ID
  OTTHUMG00000182964

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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