5HT7 Receptor/SR-7 Antibody, Cy7 Conjugated
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Catalog numberbs-12056R-Cy7
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PricePlease ask
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Size0.1ml
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Long name5HT7 Receptor/SR-7 Polyclonal Antibody, Cy7 Conjugated
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CategoryConjugated Primary Antibodies
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ConjugationCy7
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target Antigen5HT7 Receptor/SR-7
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SpecificityThis is a highly specific antibody against 5HT7 Receptor/SR-7.
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ModificationUnmodified
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Modification siteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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Subcellular locationExtracellular
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SourceKLH conjugated synthetic peptide derived from human 5HT7 Receptor/SR-7
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Tested applicationsFCM, IF(IHC-P)
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Recommended dilutionsFCM(1:20-100), IF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen backgroundSerotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. SR-3 is a ligand-gated ion channel, whereas all other known serotonin receptor subtypes are G protein-coupled receptors. SR-4 mediates widespread effects in central and peripheral nervous systems. SR-7 belongs to the superfamily of G protein-coupled receptors. The gene which encodes SR-7 maps to human chromosome 10q21-q24.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation Emission743nm/767nm
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SynonymsHT 7; 5 HT X; 5 hydroxytryptamine serotonin receptor 7 adenylate cyclase coupled; 5 hydroxytryptamine serotonin receptor 7; 5 hydroxytryptamine receptor 7; 5-HT-7; 5-HT-X; 5-HT7; 5-hydroxytryptamine receptor 7; 5HT7; 5HT7R_HUMAN; HTR7; Serotonin 5 HT 7 receptor; Serotonin receptor 7.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths.
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Additional conjugationCy7
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DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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French translationanticorps
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Gene target
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Gene symbolMSR1, MEGF10, MARCO, PIRC34, PIRC33, SRPRB, SIGMAR1, SNCG, PIRC32, SNORD114-7
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Short nameAnti-5HT7 Receptor/SR-7
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TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
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IsotypeImmunoglobulin G (IgG)
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LabelCy7
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Alternative nameAnti-5HT7 Receptor/SR-7 PAb Cy7
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namemacrophage scavenger receptor 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-08-07
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Pubmed identfication
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Classification
- CD molecules
- Scavenger receptors
- Scavenger receptor cysteine rich domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemultiple EGF like domains 10
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Synonyms gene name
- multiple EGF-like-domains 10
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Synonyms
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GenBank acession
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Locus
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Discovery year2006-03-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Scavenger receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemacrophage receptor with collagenous structure
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-11-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Scavenger receptors
- Scavenger receptor cysteine rich domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 34
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 33
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene nameSRP receptor subunit beta
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Synonyms gene name
- signal recognition particle receptor, B subunit
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-01-29
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesigma non-opioid intracellular receptor 1
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Synonyms gene
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Synonyms gene name
- opioid receptor, sigma 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-03-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesynuclein gamma
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-04-07
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Entrez gene record
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Pubmed identfication
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 32
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 114-7
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Synonyms
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Locus
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Discovery year2006-09-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data