AZ 628

• Catalog number
  B1713-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  AZ 628; AZ628; AZ-628; 3-(2-cyanopropan-2-yl)-N-[4-methyl-3-[(3-methyl-4-oxoquinazolin-6-yl)amino]phenyl]benzamide
• Description
  AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc.
• CAS Number
  878739-06-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₇H₂₅N₅O₂
• Molecular Weight
  451.53
• Cell Permeable
  Yes
• Purity
  >98%
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A new pan-Raf inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD17392577
• PubChem CID
  11676786
• PubChem CID Link
• SMILES
  CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(C)(C)C#N)NC3=CC4=C(C=C3)N=CN(C4=O)C
• InChi
  InChI=1S/C27H25N5O2/c1-17-8-9-21(31-25(33)18-6-5-7-19(12-18)27(2,3)15-28)14-24(17)30-20-10-11-23-22(13-20)26(34)32(4)16-29-23/h5-14,16,30H,1-4H3,(H,31,33)
• InChi Key
  ZGBGPEDJXCYQPH-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  628  
• Short name
  AZ 628
• Alternative name
  AZ 628

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