BMN-673

• Catalog number
  B1861-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  (8R,9S)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-8,9-dihydro-1H-pyrido[4,3,2-de]phthalazin-3(2H)-one; Talazoparib
• Description
  BMN-673 is a potent and selective PARP1/2 inhibitor with Ki values of 1.2 and 0.9 nM, respectively. It had no effect on panels of 72 receptors, ion channels, and enzymes. BMN-673 displays selective antitumor cytotoxicity and elicits DNA repair biomarkers at much lower concentrations than earlier generation PARP1/2 inhibitors.
• CAS Number
  1207456-01-6
• Structure Available
  Yes
• Molecular Formula
  C₁₉H₁₄F₂N₆O
• Molecular Weight
  380.35
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>15 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent and selective PARP1/2 inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• PubChem CID
  53345055
• PubChem CID Link
• SMILES
  CN1C(=NC=N1)C2C(N=C3C=C(C=C4C3=C2NNC4=O)F)C5=CC=C(C=C5)F
• InChi
  InChI=1S/C19H14F2N6O/c1-27-18(22-8-23-27)15-16(9-2-4-10(20)5-3-9)24-13-7-11(21)6-12-14(13)17(15)25-26-19(12)28/h2-8,15-16,25H,1H3,(H,26,28)
• InChi Key
  IUEWAGVJRJORLA-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  BMN-673  
• Short name
  BMN-673
• Alternative name
  BMN-673

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