NLGN1/NLGN2 Antibody, ALEXA FLUOR 647
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Catalog number
bs-11098R-A647
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Price
Please ask
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Size
100ul
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Long name
NLGN1/NLGN2 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
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Also known as
Anti-NLGN1/NLGN2 PAb ALEXA FLUOR 647
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Category
Conjugated Primary Antibodies
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Conjugated with
ALEXA FLUOR® 647
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
NLGN1/NLGN2
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Specificity
This is a highly specific antibody against NLGN1/NLGN2.
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Modification
Unmodified
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Modification Site
None
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NLGN1/NLGN2
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Gene ID Number
1131
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigen
Neuroligins are a family of plasma membrane proteins that possess an N-terminal hydrophobic domain, a large esterase homology domain, a single transmembrane region, a short cytoplasmic domain, and an EF-hand binding domain (1,2). Members of the neuroligin family include Neuroligin 1, Neuroligin 2 and Neuroligin 3. Neuroligins are expressed in excitatory neuronal synaptic clefts. Neuroligins play a role in the formation and remodeling of CNS synapses by binding to b-neurexins, a family of neuronal cell surface proteins. Neuroexin 1b binds to the EF-hand domain of Neuroligin 1 and requires calcium ion. Neuroligins also bind to PSD-95, which may recruit ion channels and neurotransmitter receptors to the synapses.
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Purification
Purified by Protein A.
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Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission
650nm/665nm
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Synonyms
NL1; NL2; Neuroligin 1; Neuroligin 2; Neuroligin I; Ortholog of human and rat neuroligin 2 NLGN2.
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Properties
For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-NLGN1/NLGN2 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Conjugation
Alexa Fluor, ALEXA FLUOR 647
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French translation
anticorps
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Gene target
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Gene symbol
NLGN2, NLGN1, NLGN1-AS1
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Short name
Anti-NLGN1/NLGN2
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Immunoglobulin G (IgG)
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Label
ALEXA FLUOR 647
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Alternative name
NLGN1/NLGN2 Polyclonal Antibody, ALEXA FLUOR 647
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Alternative technique
antibodies
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Alternative to gene target
neuroligin 2, NLGN2 and IDBG-24850 and ENSG00000169992 and 57555, cell adhesion molecule binding, Cell surfaces, Nlgn2 and IDBG-192156 and ENSMUSG00000051790 and 216856, NLGN2 and IDBG-634885 and ENSBTAG00000020252 and 787986
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Gene info
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Identity
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Gene
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Long gene name
neuroligin 2
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Synonyms
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GenBank acession
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Locus
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Discovery year
2001-01-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
neuroligin 1
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Synonyms
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GenBank acession
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Locus
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Discovery year
2001-01-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
NLGN1 antisense RNA 1
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Synonyms gene name
- NLGN1 antisense RNA 1 (non-protein coding)
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Locus
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Discovery year
2011-07-27
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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