Anti-CTNND2/delta 2 Catenin, ALEXA Fluor 594

• Catalog number
  GENTObs-11679R-A594
• Price
  Please ask
• Size
  100 microliters

• Type
  Conjugated Primary Antibody
• Conjugated with
  ALEXA FLUOR® 594
• Host organism
  Rabbit (Oryctolagus cuniculus)
• Target Protein Peptide
  CTNND2/delta 2 Catenin
• Specificity
  This antibody reacts specifically with CTNND2/delta 2 Catenin
• Modification
  No modification has been applied to this antibody
• Modification site
  None
• Clonality
  Polyclonal Antibody
• Clone
  Polyclonal Antibodies
• Concentration
  1ug per 1ul
• Subcellular locations
  N/A
• Antigen Source
  KLH conjugated synthetic peptide derived from human delta 2 Catenin
• Gene ID
  N/A
• Swiss Prot
  N/A
• Applications
  IF(IHC-P)
• Applications with corresponding dilutions
  IF(IHC-P)(1:50-200)
• Cross reactive species
  Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
• Cross Reactive Species details
  No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
• Background information
  The Alpha-, Beta-, Gamma-, and Delta -catenins are proteins that bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. Alpha-catenin interacts with E-cadherin associated protein and also associates with other members of the cadherin family, such as N-cadherin and P-cadherin. Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. Beta-catenin also complexes with the tumor suppressor protein APC. Gamma-catenin, also known as plakoglobin, is a protein that binds ?catenin and N-cadherin. Gamma-catenin interacts with presenilin 1 and is expressed in the brain. The gene encoding Gamma-catenin maps to human chromosome 5p15.2. A hemizygous loss of the gene encoding Gamma-catenin leads to the mental retardation associated with Cri-du-Chat syndrome. In addition, the transmembrane phosphatase PTPm associates with catenin/ cadherin complexes and may regulate complex signaling.
• Purification method
  Purified by Protein A.
• Storage
  Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
• Excitation emission
  590nm/617nm
• Synonyms
  Catenin cadherin associated protein delta 2; Catenin delta 2; Catenin delta-2; CTND2_HUMAN; CTNND 2; CTNND2; Delta catenin; Delta-catenin; GT 24; GT24; Neural plakophilin related arm repeat protein; Neural plakophilin related armadillo repeat protein; Neural plakophilin-related ARM-repeat protein; Neurojungin; NPRAP
• Also known as
  CTNND2/delta 2 Catenin Antibody
• Other name
  Anti-CTNND2/delta 2 Catenin
• Advisory
  Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Properties
  For facs or microscopy Alexa 1 conjugate.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.

• Gene target
  CTNND2/delta   Catenin  
• Gene symbol
  CTNND2
• Short name
  Anti-CTNND2/delta 2 Catenin
• Technique
  anti-, anti, antibody to, antibodies
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  CTNND2/delta 2 Catenin Antibody, ALEXA FLUOR® 594 Conjugated
• Alternative technique
  antibodies
• Alternative to gene target
  catenin (cadherin-associated protein), delta 2, GT24 and NPRAP, CTNND2 and IDBG-12568 and ENSG00000169862 and 1501, protein binding, nuclei, Ctnnd2 and IDBG-132442 and ENSMUSG00000022240 and 18163, CTNND2 and IDBG-631514 and ENSBTAG00000017222 and 523661

Gene info

• Identity
  HGNC:2516
• Gene
  CTNND2
• Long gene name
  catenin delta 2
• Synonyms gene name
  • catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
  • catenin (cadherin-associated protein), delta 2
• Synonyms
  • NPRAP
  • GT24
• Synonyms name
  • neural plakophilin-related arm-repeat protein
  • neurojungin
• GenBank acession
  • U52828
• Locus
  5p15.2
• Discovery year
  1997-06-24
• Entrez gene record
  1501
• Pubmed identfication
  • 9342840
  • 9223106
• RefSeq identity
  • NM_001332
• Classification
  • p120 catenin family
  • Armadillo repeat containing
• VEGA ID
  OTTHUMG00000090511

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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