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Human CSF2RA CRISPR Knock Out Cell Line

Human CSF2RA CRISPR Knock Out Cell Line is available 9 times from Abm crispr labs

K0515152 | Human CSF2RA CRISPR Knock Out 293 Cell Line size: 1x10^6 cells/1.0ml | 6,648.16 USD

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K0515151 | Human CSF2RA CRISPR Knock Out 293T Cell Line size: 1x10^6 cells/1.0ml | 6,648.16 USD

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K0515153 | Human CSF2RA CRISPR Knock Out A549 Cell Line size: 1x10^6 cells/1.0ml | 6,648.16 USD

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K0515154 | Human CSF2RA CRISPR Knock Out HeLa Cell Line size: 1x10^6 cells/1.0ml | 6,648.16 USD

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K0515156 | Human CSF2RA CRISPR Knock Out HepG2 Cell Line size: 1x10^6 cells/1.0ml | 6,648.16 USD

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K0515158 | Human CSF2RA CRISPR Knock Out K562 Cell Line size: 1x10^6 cells/1.0ml | 6,648.16 USD

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K0515157 | Human CSF2RA CRISPR Knock Out MCF7 Cell Line size: 1x10^6 cells/1.0ml | 6,648.16 USD

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K0515155 | Human CSF2RA CRISPR Knock Out MDA-MB-435 Cell Line size: 1x10^6 cells/1.0ml | 6,648.16 USD

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K0515159 | Human CSF2RA CRISPR Knock Out U87-MG Cell Line size: 1x10^6 cells/1.0ml | 6,648.16 USD

Catalog number K0515159
Supplier ABM CrispR
Price6,648.16 USD
Size 1x10^6 cells/1.0ml
Cell line type U87-MG
Ordering If you wish to order this product, please include the catalogue number #K0515159in your purchase order among with your shipping and billing information.
Short name CSF2RA CRISPR Knock Out U87-MG Line
Alternative name H. sapiens colony stimulating factor 2 receptor, a, low-affinity (granulocyte-macrophage) CRISPR Knock Out U87-MG cellular Line
Alternative to gene target colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage), CD116 and CDw116 and CSF2R and CSF2RAX and CSF2RAY and CSF2RX and CSF2RY and GM-CSF-R-alpha and GMCSFR and GMR and SMDP4, CSF2RA and IDBG-39400 and ENSG00000198223 and 102725415,1438, protein binding, Extracellular, Csf2ra and IDBG-182098 and ENSMUSG00000059326 and 12982, CSF2RA and IDBG-642291 and ENSBTAG00000045948 and 100336606,511847
1. Gene info
Identity2435
GeneCSF2RA
Long gene name colony stimulating factor 2 receptor alpha subunit
Synonyms gene
Synonyms gene name
  • colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
GenBank acession
Discovery year 1990-07-03
Entrez gene record1438
Pubmed identfication
Classification
  • CD molecules
  • Pseudoautosomal region 1
Havana BLAST/BLATOTTHUMG00000012533
Locus Specific Databases
2. Gene info
Identity32561
Long gene name small Cajal body-specific RNA 5
Synonyms
GenBank acession
Locus2q37.1
Discovery year 2006-03-31
Entrez gene record677775
Pubmed identfication
RefSeq identity
Classification
  • Small Cajal body-specific RNAs
Additional information
PubMedfunctional studies demonstrated GMCSF-dependent activation of IkappaB kinase activity in endothelial cells, degradation of IkappaB, and activation of NF-kappaB
receptors alphaGMR and c-Kit could interact to coordinate their signal initiation; alphaGMR inhibited c-Kit auto-phosphorylation induced by the ligand stem cell factor
The cytosolic domain of the hGM Ralpha chain is required for differentiation mediated by activation of the hGM Ralpha, beta(c) receptor complex.
used the intracellular portion of the alpha subunit of the GM-CSF receptor to search for interacting proteins and identified the 67-kDa laminin receptor as a binding partner
Observational study of gene-disease association. (HuGE Navigator)
best diffracting crystals of ternary complex were obtained using the N346Q mutation of the betac subunit. Crystals grew using polyethylene glycol 3350 with a high concentration of proline, belonged to space group P6(3)22 and diffracted to 3.3 A resolution
Results suggest that that pulmonary alveolar proteinosis can result from a genetic deficiency of the GM-CSF receptor alpha chain, encoded in the X-chromosome pseudoautosomal region 1.
Identify defective expression and function of CD116 as a distinguishing feature of IBD and implicate an associated defect in innate immune responses toward granulocyte-macrophage colony-stimulating factor.
The GM-CSF Ralpha were ubiquitously but not uniformly expressed in neurons throughout the brain and downregulation in brain in patient with alzheimenr disease.
regulatory molecule causative of aortic dissection and intramural haematoma
Product images
    #Human#.jpg
Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
NCBI number NM_006140
Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Notes Designed for Research Use Only. Manufactured in Canada.
Description For cells, cell lines and tissues in culture till half confluency.
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Species Human
Tissue cell
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