tumor protein p53 binding protein fragment [Homo sapiens]/[Mus musculus]
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Catalog number
A1094-5
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Price
Please ask
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Size
5mg
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Description
Tumor protein p53 binding protein (53BP1) has been identified as a protein that interacts with the central DNA–binding domain of p53. 53BP1 participates in DNA damage–signaling pathways and is regulated by ATM after γ-radiation. It becomes hyperphosphorylated and rapidly relocates to the sites of DNA strand breaks in response to ionizing radiation.
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Formula
C57H87N13O18
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Molecular Weight
1242.38
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Additional description
Human proteins from Homo sapiens human species. Homo is the human genus, which also includes Neanderthals and many other extinct species of hominids. Specific human epitopes are selected for human ELISA kits.
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Gene target
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Short name
tumor protein p53 binding protein [ ]/[Mus musculus]
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Isotype
Antibody fragments and scFv fragments, single chain variable fragments can be E. coli expressed. Fragment peptides for polyclonals give monoclonal like antibodies as the epitope is very small. IgG Fc and(ab)2 fragments are small and stable subunits of the antibody obtained by enzymatic digestion. Complement fragments, bp DNA fragments are common.
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Alternative name
tumor protein p53 binding protein fragment [Homo sapiens]/[Mus musculus]
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Tissue
tumor
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MeSH Data
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Name
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Concept
Scope note:
A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
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Tree numbers
- E01.370.225.500.383.910
- E01.370.225.500.388.930
- E05.200.500.383.910
- E05.200.500.388.930
- E05.242.383.910
- E05.242.417.500
- E05.337.550.200.800
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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