CX-6258

• Catalog number
  2851-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  (E)-5-chloro-3-((5-(3-(4-methyl-1,4-diazepane-1-carbonyl)phenyl)furan-2-yl)methylene)indolin-2-one
• Description
  CX-6258 is a potent pan-Pim kinases inhibitor (IC₅₀ values of 5 nM, 25 nM and 16 nM for Pim-1, Pim-2 and Pim-3, respectively). CX-6258 exhibits in vitro synergy with chemotherapeutics and robust in vivo efficacy in two Pim kinases driven tumor models.
• CAS Number
  1202916-90-2
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₆H₂₄ClN₃O₃
• Molecular Weight
  461.94
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>5 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent pan-Pim kinase inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  44545852
• PubChem CID Link
• SMILES
  CN1CCCN(CC1)C(=O)C2=CC=CC(=C2)C3=CC=C(O3)C=C4C5=C(C=CC(=C5)Cl)NC4=O
• InChi
  InChI=1S/C26H24ClN3O3/c1-29-10-3-11-30(13-12-29)26(32)18-5-2-4-17(14-18)24-9-7-20(33-24)16-22-21-15-19(27)6-8-23(21)28-25(22)31/h2,4-9,14-16H,3,10-13H2,1H3,(H,28,31)/b22-16+
• InChi Key
  KGBPLKOPSFDBOX-CJLVFECKSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  CX-6258  
• Short name
  CX-6258
• Alternative name
  CX-6258

Similar products