Phospho-CCR5(Ser349) Antibody

• Catalog number
  A1734-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  CCR5(Ser349)
• Target Alternative Name
  AM4 7, C-C chemokine receptor type 5, CC CKR 5, CCR 5, CD 195, Chemokine receptor CCR5, CHEMR13, CKR 5, CMKBR 5, FLJ78003, HIV1 fusion coreceptor, IDDM22, MIP-1 alpha receptor
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  A synthesized peptide derived from human CCR5 around the phosphorylation site of Sersine 349.
• Accession
  P51681
• Gene Id
  1234
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  1 mg/ml
• Formulation
  In phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Purification
  Affinity purified
• Application
  Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blotting, ELISA
• Application And Usages
  WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
• Description
  CCR5 a 7-transmembrane G-linked receptor for a number of inflammatory C-C type chemokines including MIP-1-alpha, MIP-1-beta and RANTES. Transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (along with CD4) for HIV-1 R5 isolates. Interacts with PRAF2. Interacts with HIV-1 surface protein gp120. Efficient ligand binding to CCL3/MIP-1alpha and CCR4/MIP-1beta requires sulfation, Oglycosylation and sialic acid modifications. Glycosylation on S6 is required for efficient binding of CCL4.
• Storage Condition
  -20°C
• Shipping Condition
  Gel Pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  True
• Immunocytochemistry Verified
  False
• Immunofluorescence Verified
  True
• Immunoprecipitation Verified
  False
• FACS Verified
  False
• ELISA Verified
  True
• ChIP Verified
  False
• Dot Blot Verified
  False
• Flow Cytometry Verified
  False
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Phospho-CCR5   Ser349  
• Gene symbol
  CCR5
• Short name
  Phospho-CCR5(Ser349) Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  IgG
• Alternative name
  phosphorilated-chemokine (C-C motif) receptor 5 (gene/pseudogene)(Ser349) (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  chemokine (C-C motif) receptor 5 (gene/pseudogene), CC-CKR-5 and CCCKR5 and CCR-5 and CD195 and CKR-5 and CKR5 and CMKBR5 and IDDM22, CCR5 and IDBG-30229 and ENSG00000160791 and 1234, chemokine (C-C motif) ligand 5 binding, Cell surfaces, CCR5 and IDBG-646247 and ENSBTAG00000008099 and 497017

Gene info

• Identity
  HGNC:1606
• Gene
  CCR5
• Long gene name
  C-C motif chemokine receptor 5
• Synonyms gene
  • CMKBR5
• Synonyms gene name
  • chemokine (C-C motif) receptor 5
  • chemokine (C-C motif) receptor 5 (gene/pseudogene)
  • C-C motif chemokine receptor 5 (gene/pseudogene)
• Synonyms
  • CKR-5
  • CC-CKR-5
  • CKR5
  • CD195
  • IDDM22
• Locus
  3p21.31
• Discovery year
  1996-05-15
• Entrez gene record
  1234
• Pubmed identfication
  • 8639485
  • 9284370
  • 20210993
• RefSeq identity
  • NM_000579
• Classification
  • C-C motif chemokine receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000133481

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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