FTO Antibody, ALEXA FLUOR 647

• Catalog number
  bs-7056R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  FTO Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-FTO PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  FTO
• Specificity
  This is a highly specific antibody against FTO.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  180-230/505
• Subcellular location
  Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fat mass and obesity-associated protein
• Gene ID Number
  79068
• Swiss Prot
  Q9C0B1
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Has no activity towards 1-methylguanine. Has no detectable activity towards double-stranded DNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Contributes to the regulation of body size and body fat accumulation.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  ALKBH9; Alpha-ketoglutarate-dependent dioxygenase FTO; Fat mass and obesity-associated protein; FTO; KIAA1752
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-FTO exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  FTO  
• Gene symbol
  FTO-IT1, FTO
• Short name
  Anti-FTO
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  FTO Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies
• Alternative to gene target
  fat mass and obesity associated, FTO and IDBG-31147 and ENSG00000140718 and 79068, DNA-N1-methyladenine dioxygenase activity, nuclei, Fto and IDBG-179938 and ENSMUSG00000055932 and 26383, FTO and IDBG-631892 and ENSBTAG00000012501 and 618622

Gene info

• Identity
  HGNC:43758
• Gene
  FTO-IT1
• Long gene name
  FTO intronic transcript 1
• Synonyms gene name
  • FTO intronic transcript 1 (non-protein coding)
• GenBank acession
  • CA450585
• Locus
  16q12.2
• Discovery year
  2012-02-22
• Entrez gene record
  100505692
• RefSeq identity
  • NR_103838
• Classification
  • Intronic transcripts

Gene info

• Identity
  HGNC:24678
• Gene
  FTO
• Long gene name
  FTO alpha-ketoglutarate dependent dioxygenase
• Synonyms gene name
  • fat mass and obesity associated
  • FTO, alpha-ketoglutarate dependent dioxygenase
• Synonyms
  • KIAA1752
  • MGC5149
  • ALKBH9
• Synonyms name
  • alkB homolog 9
  • alpha-ketoglutarate-dependent dioxygenase
• GenBank acession
  • BC003583
• Locus
  16q12.2
• Discovery year
  2007-04-12
• Entrez gene record
  79068
• Pubmed identfication
  • 17434869
  • 17991826
  • 22002720
• RefSeq identity
  • NM_001080432
• Classification
  • Alkylation repair homologs
• VEGA ID
  OTTHUMG00000158780

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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