anti- HUS1 antibody

• Catalog number
  FNab04082
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants.
• Immunogen
  HUS1 checkpoint homolog (S. pombe)
• Calculated MW
  Refer to figures
• Uniprot ID
  O60921
• Specificity
  Human, Mouse, Rat
• Tested Application
  ELISA, IHC, WB
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
• Image1
  Immunohistochemistry of paraffin-embedded human colon cancer using FNab04082(HUS1 antibody) at dilution of 1:50
• Image4
  BxPC-3 cells were subjected to SDS PAGE followed by western blot with FNab04082(HUS1 antibody) at dilution of 1:0
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HUS1  
• Gene symbol
  HUS1
• Short name
  anti- HUS1 antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- HUS1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:5309
• Gene
  HUS1
• Long gene name
  HUS1 checkpoint clamp component
• Synonyms gene name
  • HUS1 (S. pombe) checkpoint homolog
  • HUS1 checkpoint homolog (S. pombe)
• Synonyms name
  • hus1+-like protein
• GenBank acession
  • Y16893
• Locus
  7p12.3
• Discovery year
  1998-07-31
• Entrez gene record
  3364
• Pubmed identfication
  • 9878245
  • 9524127
  • 11944979
• RefSeq identity
  • NM_004507
• Classification
  • Checkpoint clamp complex
• VEGA ID
  OTTHUMG00000155645

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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