Recombinant Human Neuroplastin/NPTN Protein(C-6His)

• Catalog number
  PKSH032801-10µg
• Price
  Please ask
• Size
  10µg

• Synonym
  Neuroplastin; Stromal Cell-Derived Receptor 1; SDR-1; NPTN; SDFR1; SDR1
• Activity
  NA
• Sequence
  Gln29-His220
• Fusion tag
  C-6His
• Accession
  Q9Y639
• Expressed Host
  Human cells
• Shipping
  The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
• Purity
  ＞95% as determined by reducing SDS-PAGE.
• Endotoxin
  ＜1.0 EU per µg as determined by LAL test.
• Stability and Storage
  Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
• Mol Mass
  22.7 kDa
• AP Mol Mass
  40 kDa
• Formulation
  Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
• Background
  Neuroplastin (NPTN) is a 52-57 kDa member of the Ig-superfamily. Neuroplastin likely serves as a cell adhesion molecule, and is widely expressed in multiple tissues. Human Neuroplastin is 282 amino acids that contions two Ig-like domains and a 38 aa cytoplasmic region. Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. Neuroplastin may also regulate neurite outgrowth by activating the FGFR1 signaling pathway. It may play a role in synaptic plasticity.
• Technical data
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Neuroplastin/NPTN   Protein   C-6His  
• Gene symbol
  NPTN-IT1, NPTN
• Short name
  Recombinant Neuroplastin/NPTN Protein(C-6His)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Neuroplastin/neuroplastin Protein(C-6His)
• Alternative technique
  rec
• Alternative to gene target
  neuroplastin, NPTN and IDBG-21125 and ENSG00000156642 and 27020, cell adhesion molecule binding, Plasma membranes, Nptn and IDBG-172134 and ENSMUSG00000032336 and 20320, BT.45355 and IDBG-645643 and ENSBTAG00000008218 and 540039

Gene info

• Identity
  HGNC:45091
• Gene
  NPTN-IT1
• Long gene name
  NPTN intronic transcript 1
• Synonyms gene name
  • NPTN intronic transcript 1 (non-protein coding)
• Synonyms
  • lncRNA-LET
• Synonyms name
  • long non-coding RNA, low expression in tumor
• GenBank acession
  • AK055007
• Locus
  15q24.1
• Discovery year
  2013-02-11
• Entrez gene record
  101241892
• Pubmed identfication
  • 23395002
• RefSeq identity
  • NR_103844
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000189514

Gene info

• Identity
  HGNC:17867
• Gene
  NPTN
• Long gene name
  neuroplastin
• Synonyms gene
  • SDFR1
• Synonyms gene name
  • stromal cell derived factor receptor 1
• Synonyms
  • SDR1
  • GP55
  • GP65
  • np65
  • np55
• GenBank acession
  • AF035287
• Locus
  15q24.1
• Discovery year
  2002-11-21
• Entrez gene record
  27020
• Pubmed identfication
  • 8619474
  • 9110174
• RefSeq identity
  • NM_012428
• Classification
  • Basigin family
  • I-set domain containing
• VEGA ID
  OTTHUMG00000137586

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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